A 46 year old woman has had increasing weakness and loss of sensation - ProProfs
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A 46-year-old woman has had increasing weakness and loss of sensation in the lower extremities for the past 5 months. She comes to the physician because she has been unable to walk without assistance for the past week. On physical examination, there is 4/5 motor strength in the right lower extremity and 3/5 motor strength in the left lower extremity. There is bilateral loss of sensation to light touch from the lateral midthigh distally. MRI of the spine shows a 1 × 4 cm lesion in the filum terminale. The mass is removed. Microscopically, the mass is composed of cuboidal cells around papillary cores in a myxoid background. Which of the following was most likely present in this patient?



A. Choroid plexus papilloma
B. Ependymoma
C. Meningioma
D. Metastatic transitional cell carcinoma
E. Neurofibroma
F. Pilocytic astrocytoma
G. Schwannoma

This question is part of

Pathology Review ch 28 CNS prt 3

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1 Answer

John Smith

John Smith

Answered on Sep 09, 2016

Ependymoma-(b) this patient had the myxopapillary variant of ependymoma, which is more common in adults than in children. the tumors that arise in the ventricles (usually the fourth ventricle) are more common in the first 2 decades of life. choroid plexus papillomas are rare tumors that arise in the cerebral ventricles. meningiomas most often arise in the cranial cavity and have plump, pink, round to spindle-shaped cells, often with psammoma bodies. metastases to the spinal cord are uncommon. neurofibromas are more likely to arise in peripheral nerves, although in neurofibromatosis type 1, they can arise in many sites. a pilocytic astrocytoma is a common pediatric primary intracranial neoplasm; it arises in the posterior fossa. a schwannoma most often occurs in cranial nerve viii, although neurofibromatosis may be associated with multiple schwannomas. bp7 834bp8 884pbd7 1405pbd8 13341335
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