A term infant is born to a 32-year-old woman whose pregnancy was uncomplicated. A newborn physical examination
shows a small lower lumbar skin dimple with a protruding tuft of hair. A radiograph shows that the underlying L4 vertebra
has lack of closure of the posterior arches. What is the most likely diagnosis?
A. Dandy-Walker malformation B. Spina bifida occulta C. Tuberous sclerosis D. Arnold-Chiari malformation E. Meningomyelocele
Spina bifida occulta-(b) spina bifida occulta is the mildest form of neural tube defect. it is characterized by defective closure of the vertebral
arches with intact meninges and spinal cord. a radiograph may show its presence in 20% of the population. dandy-walker
malformation is detected by ultrasound evidence of a cyst in the fourth ventricle and agenesis of the cerebellar vermis.
tuberous sclerosis is a rare disease that causes firm hamartomatous tubers in the cortex. in an arnold-chiari
malformation, there is a small posterior fossa and extension of the cerebellum into the foramen magnum and a lumbar
meningomyelocele. meningomyeloceles are open neural tube defects.
bp7 821822bp8 872pbd7 1354pbd8 1284