What is the reason for the purpuric rash? - ProProfs Discuss
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What is the reason for the purpuric rash?



A. IgM immune complexes that induce vaculitis
B. Macrophage activation that triggers cytokine secretion with subsequent vascular leakage
C. Histamine release by mast cells in the skin
D. IgA immune complexes that induce vasculitis
Asked by Ewing, Last updated: Mar 15, 2018

This question is part of

Block 11 - Week 12 - Vasculitis

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1 Answer

John Smith

John Smith

Answered on Sep 09, 2016

Iga immune complexes that induce vasculitis-d. henoch-schonlein purpura1. vasculitis due to lga immune complex deposition; most common vasculitis inchildren2. presents with palpable purpura on buttocks and legs, gi pain and bleeding, andhematuria (iga nephropathy); usually occurs following an upper respiratorytract infection3. disease is self-limited, but may recur; treated with steroids, if severeiga associated vasculitischildren (most common vasculitis in kids)follows infection (viral, strep a)iga and complement immune depositsinvolves skin, gi, renal, jointsself-limited
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