Hemosiderin in hepatocytes-each unit of blood contains about 250 mg of iron. the body has no mechanism for getting rid of excess iron. about10 to 20 mg of iron per day is lost with normal desquamation of epithelia; menstruating women lose slightly more. anyexcess iron becomes storage iron, or hemosiderin. over time, hemosiderosis involves more and more tissues of the body,particularly the liver. initially, hemosiderin deposits are found in kupffer cells and other mononuclear phagocytes in thebone marrow, spleen, and lymph nodes. with great excess of iron, liver cells also accumulate iron. steatosis usuallyoccurs with ingestion of hepatotoxins, such as alcohol. bilirubin, a breakdown product of blood, can be excreted in the bileso that a person does not become jaundiced. glycogen storage diseases are inherited and present in childhood. amyloidis an abnormal protein derived from a variety of precursors, such as immunoglobulin light chains.bp7 20bp8 26pbd7 3940pbd8 3637
