Which of the following mechanisms for transmembrane transport of - ProProfs Discuss
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Which of the following mechanisms for transmembrane transport of drugs exhibits selectivity, competition, saturability and does not require metabolic energy ?



A. Aqueous diffusion
B. Lipid diffusion
C. Facilitated diffusion
D. Active transport
E. Endocytosis

This question is part of block 9 pharm drug absorbtion w exp

Asked by Kayla, Last updated: Aug 08, 2020

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John Smith

John Smith

Answered Sep 09, 2016

Facilitated diffusion-1) learning objective: describe the main features of facilitated diffusion of drugs across cellmembranes.answer: cfacilitated diffusion is a carrier mediated transport that can carry across cell membranecompounds too large or too insoluble in lipids to permeate by aqueous or lipid diffusion.facilitated diffusion is:a) passive (t does not require metabolic energy by the cell).b) selective (the carrier is specific for a given drug, or for other drugs with similar conformationalstructure).c) saturable (when the number of molecules to be carried exceed the number of carrier moleculesthe process becomes saturated and therefore is no longer proportional to the concentrationgradient).d) subject to inhibition (competitive inhibition can occurs if there is a second ligand which can bindto the carrier)a, b) these transport systems are passive but do not exhibits selectivity, competition andsaturability.d, e ) these are active transport systems.
 

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