Which of the following accurately describe the chronological set of descriptive changes that occur in the endometrium during the menstrual cycle?
A. Proliferation, secretion, decidualization, menstruation B. Decidualization, menstruation, secretion, proliferation C. Menstruation, secretion, decidualization, proliferation D. Menstruation, decidualization, proliferation, secretion E. Secretion, menstruation, proliferation, decidualization
Proliferation, secretion, decidualization, menstruation-the endometrium expresses estrogen and progesterone receptors, and therefore the ovarian hormones directly influence endometrial changes. the endometrium proliferates rapidly under the influence of estradiol, and therefore this is termed the proliferative phase. progesterone induces glandularsacculation and stimulates the production of secretory compounds, and therefore this phase is termed the secretory phase. extended exposure to progesterone cause the endometrial stromal cells to differentiate, a process termed decidualization. in a normal menstrual cycle, the corpus luteum stops secreting progesterone after 1216 days, and the subsequent progesterone withdrawal induces sloughing of the endometrial functionalis zone during menstruation. regardless of which phase you list first, the sequence of events is always constant (i.e. proliferation always precedes secretion, which always precedes decidualization, etc.).