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Dr. Sands What mutational event is often associated with Burkitt’s lymphoma?



A. The ras protooncogene is mutated at one nucleotide so that it is less able to hydrolyze bound GTP
B. The 3’ end of the c-src gene is deleted so that the SRC protein is always activated.
C. There is a translocation of the c-myc gene to one of the immunoglobulin loci.
D. There is a deletion of the p16 gene which allows unregulated passage through the G1 restriction point.
E. EBV causes the Her-2 protein to dimerize without a ligand binding to the receptor
Asked by Christopher, Last updated: Dec 18, 2019

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Block 7 Pace quiz 2 part 1

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John Smith

John Smith

Answered Sep 09, 2016

There is a translocation of the c-myc gene to one of the immunoglobulin loci.-to assure the rapid loss of c-fos and c-myc after their induction in normal cells, both proteins and their corresponding mrnas are intrinsically unstable. some of the changes that turn c-fos from a normal gene to an oncogene involve loss of sequences in the gene that make the fos mrna and protein short-lived. conversion of the c-myc proto-oncogene into an oncogene can occur by several different mechanisms. in cells...Read More
 

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