Amantadine is used to treat a group of side effects (called parkinsonian side effects) that include tremors, difficulty walking, and slack muscle tone. These side effects may occur in patients who are taking antipsychotic medications used to treat mental disorders such as schizophrenia . An unrelated use of amantadine is in the treatment of viral infections of some strains of influenza A.
Some medicines, called antipsychotic drugs, that are used to treat schizophrenia and other mental disorders can cause side effects similar to the symptoms of Parkinson's disease.
Amantadine is available in 100-mg tablets and capsules, as well as a syrup containing 50 mg of amantadine in each teaspoonful. For the treatment of drug-induced parkinsonian side effects, amantadine is usually given in a dose of 100 mg orally twice a day.
Amantadine (symmetrel) -rationale: amantadine is an anticholinergic drug used to relieve drug-induced extrapyramidal adverse effects, such as muscle weakness, involuntary muscle movement, pseudoparkinsonism, and tardive dyskinesia. other anticholinergic agents used to control extrapyramidal reactions include benztropine mesylate (cogentin), trihexyphenidyl (artane), biperiden (akineton), and diphenhydramine (benadryl). perphenazine is an antipsychotic agent; doxepin, an antidepressant; and chlorazepate, an antianxiety agent. because these medications have no anticholinergic or neurotransmitter effects, they dont alleviateextrapyramidal reactions.