Which of the following statements concerning the treatment of gout is true?
A. Colchicine can be safely used in patients with chronic renal insufficiency B. Allopurinol increases uric acid elimination and is useful during an acute gouty attack C. Intramuscular injections of ACTH are useful if NSAIDs are contraindicated D. Treatment with NSAIDs should continue for at least one week after symptoms have abated E. There is a high likelihood that a single administration of IM ACTH may lead to suppression of the hypothalamic-pituitary-adrenomedullary axis
Intramuscular injections of ACTH are valuable if NSAIDS are contraindicated-indomethacin is the most normally utilized NSAID and should proceed for 24 hours after the side effects subside. colchicine hinders microtuble arrangement and obstructs the provocative reaction to precious stones in the joint. Colchicine is contraindicated in patients with hematologic, renal, and hepatic deficiency. Oral prednisone is valuable in safe cases and intra-articular infusion of steroids might be compelling for people with just 1 or 2 joints included once septic joint pain has been avoided.
ACTH (40-80 iu im) is a valuable contrasting option to the above treatments. With just a solitary organization, hypothalamic-pituitary-adrenomedullary pivot concealment ought not occur. Long term treatment of gout is intended to diminish serum uric corrosive by either diminishing creation (allopurinol) or expanding discharge (probenecid). Unending prophylactic specialists ought not be halted or started amid an intense assault
Intramuscular injections of acth are useful if nsaids are contraindicated-indomethacin is the most commonly used nsaid and should continue for 24 hours after the symptoms abate. colchicine inhibits microtuble formation and impedes the inflammatory response to crystals in the joint. colchicine is contraindicated in patients with hematologic, renal, and hepatic insufficiency. oral prednisone is useful in resistant cases and intra-articular injection of steroids may be effective for individuals with only 1 or 2 joints involved once septic arthritis has been excluded. acth (40-80 iu im) is a useful alternative to the above therapies. with only a single administration, hypothalamic-pituitary-adrenomedullary axis suppression should not occur.long term therapy of gout is aimed to decrease serum uric acid by either decreasing production (allopurinol) or increasing excretion (probenecid.) chronic prophylactic agents should not be stopped or initiated during an acute attack. (chapter 114)