Which of the following do class III MHC genes encode for? - ProProfs Discuss
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Which of the following do class III MHC genes encode for?



A. CD4+ T cells
B. CD8+ T cells
C. Compliment molecules
D. Cytokine molecules
E. C & D

This question is part of Immunology quiz- Major Histocompatibility Complex (MHC)
Asked by Coulter, Last updated: Jan 09, 2018

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3 Answers

J. Emmerich

J. EmmerichWeb Content Writer, New York City
Web Content Writer, New York City

Answered on Feb 21, 2019

Correct answer is option E
Class III MHC genes have immune related functions. These genes encode for some complement proteins, cytokines and heat shock proteins. The MHC class III genes have the highest gene density but some of the genes are not involve in the immune systems.

Class I MHC molecules are found on all nucleated cells in the body and the bind to CD 8+ T cells. The MHC I gene encodes for CD 8+ T cells.

Class II MHC molecules are found on antigen presenting cells, macrophages, dendritic cells and B cells. These cells bind to CD 4+ T cells. The MHC II gene encodes for CD4+ T cells.

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j. Goodman

J. GoodmanWeb Content Writer, San Antonio
Web Content Writer, San Antonio

Answered on Oct 23, 2018

Option E - C & D
class III MHC genes encode for compliment molecules and cytokine molecules.
Class I MHC gene encodes for CD8+ T cells
Class II MHC gene encodes for CD4+ T cells.

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John Smith

John Smith

Answered on Jun 11, 2017

Compliment molecules
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