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Which precursor molecule would serve as the substrate that formed the first nucleotide in segment E if adenine is the first base on thee template strand corresponding to the initiation point for segment E?





A. DUTP
B. UTP
C. DTTP
D. TTP
E. DTMP

This question is part of Block 1 DNA-RNA mini 1
Asked by Chachelly, Last updated: Mar 31, 2020

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3 Answers

L. Cooper

Analyst by profession but writer by heart.

L. Cooper, Data Analyst, MCA, Newcastle

Answered Nov 01, 2019

The correct answer to this question is option C – DTTP From the image above, we can see a replication fork. This clearly states that the on-going process is DNA replication and not RNA transcription. DNA replication is a semiconservative process that occurs in 5’ to 3 ‘direction. It involves both leading and lagging strands.

The leading strands start from 5’ direction, and the lagging strand faces the 3’ direction. If adenine is the first nucleoside triphosphate molecule added on the 5’ end, then the precursor molecule that would serve as the substrate that formed the first nucleotide in segment E is DTTP (deoxythymidine triphosphate). Options A and B are wrong because uracil is not a nucleotide present in DNA. Therefore, it cannot be the substrate formed. Only triphosphate nucleosides are added in DNA replication, making other options wrong.

 

John Adney

John Adney

Answered Sep 17, 2017

This picture shows a replication fork with leading and lagging strands, making this DNA replication, not RNA transcription. So, the base would be dTTP, not UTP, since this is DNA not RNA.

 

John Smith

John Smith

Answered Apr 15, 2017

Utp
 

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