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What is the main reason for administering allopurinol as part of the client's chemotherapy? A child is undergoing remission induction therapy to treat leukemia. Allopurinol is included in the regimen.



A. Prevent metabolic breakdown of xanthine to uric acid
B. Prevent uric acid from precipitating in the ureters
C. Enhance the production of uric acid to ensure adequate excretion of urine
D. Ensure that the chemotherapy doesn’t adversely affect the bone marrow

This question is part of NCLEX Sample Questions for Pediatric Nursing 3
Asked by RN pedia, Last updated: Jan 01, 2020

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2 Answers

M. Krasinski

M. Krasinski, Content Writer, Columbus

Answered Oct 11, 2018

Allopurinol is a medicine with one purpose. It decreases the uric acid that is produced in your body. When the uric acid builds up too much, it can cause kidney stones to produce. These are very painful. So, even though this acid is naturally created within the body, too much of it cause problems. The main reason for administering allopurinol would be if someone has kidney stones or gout. A patient may be undergoing chemotherapy due to having cancer.

If a child was undergoing remission induction therapy to treat leukemia, allopurinol may be given to this child. It is given to the child because it may prevent the metabolic breakdown of xanthine which causes uric acid. Then after a while the child may have to stop taking it if the acid is under control.

 

John Smith

John Smith

Answered Apr 06, 2017

Prevent metabolic breakdown of xanthine to uric acid

The massive cell destruction resulting from chemotherapy may place the client at risk for developing renal calculi; adding allopurinol decreases this risk by preventing the breakdown of xanthine to uric acid. Allopurinol doesnt act in the manner described in the other options.
 

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