Chemotherapy is a common treatment for cancer patients. However, there is a drug that is used in chemotherapy that people may not be aware of. It is called Cisplatin. This helps with a bunch of different cancers including testicular, lung, bladder, breast, cervical and neuroblastoma, to name a few. Taking these drugs may treat or stop the cancer, but there are side effects to taking this drug including kidney damage and nerve damage.
One of the things that people are usually not aware of and it may sound strange is that this drug interferes with DNA. Its replication of DNA is what is affected and specifically includes the intrastrand cross-links and adducts. Another drug used is Oxaliplatin, but it is not used as much.
Cisplatin crosslinks DNA in several different ways, interfering with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair proves impossible (from Wikipedia)