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What SI the Extracellular fluid (ECF) volume of the women after she has gone through the following procedure?
One gram of mannitol was injected into woman. After equilibration, a plasma sample had a mannitol concentration of 0.08 g/L. During the equilibration period, 20% of the injected mannitol was excreted in the urine.

What SI the Extracellular fluid (ECF) volume of the women after she has gone through the following procedure? <br/>One gram of mannitol was injected into woman. After equilibration, a plasma sample had a mannitol concentration of 0.08 g/L. During the equilibration period, 20% of the injected mannitol was excreted in the urine.

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A. Extracellular fluid (ECF) volume is 1 L
B. Intracellular fluid (ICF) volume is 1 L
C. ECF volume is 10 L
D. ICF volume is 10 L
E. Interstitial volume is 12.5 L

This question is part of Block 6 Renal physiology BRS w expl prt 1
Asked by Chachelly, Last updated: May 22, 2020

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John Smith

John Smith

Answered Mar 10, 2017

ECF volume is 10 L

Mannitol is a marker substance for the extracellular fluid (ECF) volume. ECF volume = amount of mannitol/concentration of mannitol = 1 g - 0.2 g/0.08 g/L = 10 L.
 

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