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How does transcription begin?



A. It doesn t, transcription doesn t exist
B. When RNA polymerase binds to a sigma to create a holoenzyme and the sigma guides the RNA polymerase to certain locations where transcription should begin
C. Some dude brings a flag and says \Hey! Over here!\
D. The non-template strand signals to the binding receptor that a phospodiester bond is present and ready for action
E. The RNA polymerase binds to a coding strand located downstream

This question is part of Biology-Transcription and Translation
Asked by Wyatt Williams, Last updated: May 22, 2020

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1 Answer

John Smith

John Smith

Answered Dec 15, 2016

When RNA polymerase binds to a sigma to create a holoenzyme and the sigma guides the RNA polymerase to certain locations where transcription should begin

The holoenzyme is made up of a core enzyme (RNA polymerase) and a detachable protein subunit called a sigma. The holoenzyme creates an enviroment in which the sigma guides the RNA polymerase to the site where transcription should take place. The locations where the sigma guides the RNA pol are called promoters.
 

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