What is true about Cefepime? - ProProfs Discuss
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What is true about Cefepime?



A. Is the only 4th generation cephalosporin
B. Is more resistant to B-lactamase and can only be given parenterally
C. Has antipseudomonal activity and has better G+ coverage
D. Is excreted renally
E. All of the above

This question is part of Antibacterial agents quiz
Asked by Rita.niyigena, Last updated: Jul 13, 2020

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3 Answers

ra_tkin

Ra_tkin

Answered Dec 01, 2016

Cefopirome is also a 4th generation cef
1
 

V. Barnes

V. Barnes

Answered May 10, 2018

Cefepime is a fourth-generation cephalosporin antibiotic. Cefepime has an extended spectrum of activity than the third-generation agents against Gram-positive and Gram-negative bacteria, with greater activity against both types of organisms.

In a meta-analysis held in 2007, suggestions were made on how data of trials were combined. Mortality was increased in people who treated with cefepime compared with other β-lactam antibiotics. The United State Food and Drug Administration in response, performed their own meta-analysis which did not find any mortality difference.

Bristol-Myers Squibb developed Cefepime and was marketed in the beginning of 1994. It is now available as a generic drug and sold under a variety of trade names nationwide.

 

John Smith

John Smith

Answered Dec 02, 2016

All of the above
 

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