What is the function of DNA polymerase III? - ProProfs Discuss
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What is the function of DNA polymerase III?







This question is part of DNA Replication
Asked by Wyatt Williams, Last updated: Jul 01, 2020

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3 Answers

A. Daniels

A. Daniels, Professor, San Diego

Answered Apr 09, 2019

The function of DNA Polymerase III is that it performs 5'-3' polymerase function, which helps transcribe DNA into RNA. It can also proofread any mistakes made during replication. It was discovered in 1970 by biochemist Thomas Kornberg and Malcolm Gefter. There are three functions of DNA Polymerase III.

The first is that it adds deoxyribonucleaosde triphosphates to the DNA strand. Its; second function is catalyzing phosphodiester bonds. The third and final function is that the DNA polymerase III proofreads each deoxyribionucleotide. DNA Polymerase III is also a componet of the replisome, which is responsible for carrying out the replication of DNA.

 

John Adney

John Adney

Answered Dec 15, 2016

5'; 3'; opposite, 3', 5'
 

John Smith

John Smith

Answered Nov 21, 2016

3 , 5 , opposite, 5 , 3
 1

John Adney

Should be the other way around (5' to 3' for leading strand, 3' to 5' for lagging strand

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