What is the difference between Novolog and Humalog? - ProProfs Discuss
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What is the difference between Novolog and Humalog?

Asked by R. Barnes, Last updated: Feb 03, 2024

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D. Peter

D. Peter

Apart from developing codes, I also spend some time in quality writing.

D. Peter
D. Peter, Software Developer, B.E (Bachelor of Engineering), Mexico

Answered Nov 08, 2019

There are certain differences between NovoLog and Humalog. For those who do not know, these are medications that are used by people in order to control their diabetes. Humalog is being used by adults who have Type 1 Diabetes, while NovoLog is prescribed to those who are two years old and older.

NovoLog tends to be work slightly faster than Humalog, which works in about 15 minutes. Another main difference between the two is the ability of these two to be diluted. NovoLog can be diluted while Humalog cannot be diluted at all. Take note that both these medications are injectable.

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D. Loukas

D. Loukas

Calculating, Processing, Integrating, Differentiating are what intrigues me the most in a very beautiful way.

D. Loukas
D. Loukas, Maths Professor, Diploma in Mathematics, Beverly hills, California

Answered Nov 04, 2019

Insulin lispro (Novolog) was the first insulin analog that has been used clinically. The difference from insulin is that there is a switch between amino acid lysine B28 a proline B29. The formulation as a hexameric solution that is available in vials. It is absorbed fast into the body and has a shorter duration of effect in terms of decreasing blood sugar levels. This solution is usually used in patients with raised blood sugar, particularly after eating a meal. This condition is called prandial hyperglycemia.

Because of its speedy action and short duration of systematic effects, it is usually dispensed before a meal or up to 15 mins right after. Insulin Aspart is also named after it’s amino acid structure. Insulin Aspart is also hexameric in the formulation. Rapid drug release and short systematic effects may occur, and the drug is more commonly used among adult patients with type 1 diabetes.

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