When is chemotherapy not useful in cancer treatment?

Chemotherapy is contraindicated in cases of infection (chemotherapeutic agents are immunosuppressive). Recent surgery (chemotherapeutic agent may retard the healing process). Impaired renal and hepatic function (drugs are nephrotoxic and hepatotoxic). recent radiation therapy (immunosuppressive treatment). Pregnancy (drugs can cause congenital defects) and bone marrow depression (chemo. Agents may aggravate the condition).