Which mutation would substitute TAA, TAG or TGA in place of an - ProProfs Discuss
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Which mutation would substitute TAA, TAG or TGA in place of an expressed codon?

Asked by Atateye, Last updated: Apr 09, 2024

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5 Answers

C. Perez

C. Perez

Just getting better day by day

C. Perez
C. Perez, Writer, Writer, Cleveland

Answered Feb 18, 2021

The correct answer to this question is a nonsense mutation. A nonsense mutation refers to a type of DNA sequence that produces an unfinished and shorter protein product. A nonsense mutation is formed when nucleotide sequences, during protein synthesis, are replaced by stop codons.

Examples of these stop codons are TAA, TAG, or TGA. Most times, stop codons are also known as nonsense codons. They are called stop codons because they point to the end of protein synthesis. As a result, what comes as the product is a shortened protein.

Generally, codons are meant to code for specific amino acids, but when stop codons are introduced, they stop this process by stopping the translation of the transcribed mRNA. This is because the resulting protein will be shorter than the rest, and it will also form an incomplete protein. This type of mutation results in proteins that are not functional.

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J. Shatner

J. Shatner

J. Shatner
J. Shatner, Content writer, Boston

Answered Feb 18, 2021

Nonsense mutation. It is a type of genetic defect in which an amino acid codon is substituted by TGA, TAG, or TAA stop codon. A genetic code that indicates the end of protein manufacturing inside the cell is a stop codon. The three stop codons are nucleotide base triplets that present an integral role in intracellular protein synthesis.

Physiological and anatomical changes are possible if a stop codon is in the incorrect position or a DNA or RNA strand. It could also be if the sequence has been altered and is a type of mutation in which the alleged mutation in the DNA sequence is suddenly stopped. The chain is abruptly halted because of the chain-terminating codon that appears. Nonsense mutation can also be referred to as termination codons.

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C. Reyes

C. Reyes

C. Reyes
C. Reyes

Answered Feb 12, 2021

Nonsense mutation is the answer to this question. When you say nonsense mutation, this is known to be a single base pair that will lead to a stop codon. This is known to be a DNA sequence that will eventually result in a protein product that is still unfinished.

Take note that the DNA sequence will be composed of different smaller molecules that will be called nucleotides. Take note that an unfinished protein product cannot be used properly. The nonsense mutation will lead to a non−functional protein. Nonsense mutation can be considered to be harmful because it can make some changes to the body that cannot be considered healthy.

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Ken Wilson

Ken Wilson

Want to learn new things and share my knowledge

Ken Wilson
Ken Wilson, Marketing Analyst, MBA, Miami

Answered Jan 03, 2019

The answer to this is a nonsense mutation. This is a type of mutation wherein the supposed mutation in the sequence of DNA is suddenly halted. This means that the chain is suddenly stopped because of the chain-terminating codon that appears.

The protein that is formed because of this mutation is usually shorter and it is obviously incomplete which means that the protein that has been formed is also non-functional.

The amino acids are unable to complete their normal sequence because of this mutation. There are different gene mutations that may occur that will usually result in different health conditions.

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atateye10

atateye

atateye10
Atateye

Answered Sep 10, 2018

Nonsense mutation
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