Macrophages are the type of Antigen Presenting Cells (APC) that are critical in the uptake and presentation of antigen to T cells. APC are specialized cells that show the antigen complex on their surfaces with major histocompatibility complexes (MHCs).
Macrophages, B cells and dendritic cells are termed “professional APC” as they present antigen to helper T cells. Macrophages are stimulated by interferon-gamma, which is secreted by T cell. This, in turn, causes the expression of MHC class II on the surface of macrophages and the secretion of many costimulatory molecules. Macrophages can engulf and phagocytose fragments of antigen and present them to helper T cells.
W. WrightBiology student, Biology student, Astoria
Biology student, Biology student, Astoria
Answered on Apr 24, 2019
The answer to this is Macrophage. Are you wondering why this is the term used for this antigen? The word has been formed from two Greek words that mean “big eaters”. This type of white blood cell will make sure that the different debris, foreign substances, and so much more will be removed from the body so that they will not cause anything worse.
This will “eat” the viruses, bacteria, parasites, and fungi that do not belong in the body so that the body can stay healthy. It is obvious that the macrophage may not do exactly what it is supposed to do. It may not have the ability to get rid of the foreign substances in the body.