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Which of the following genetic principles best explains the findings in this family? A 6-year old boy is found to have almond-shaped eyes, temperature instability, mental retardation, hyperphagia, and obesity. Cytogenetic analysis shows a balanced translocation involving chromosome 15q11-q13. His father and paternal aunt are found to have an identical balanced translocation. His aunt’s 5-year old daughter has a history of inappropriate laughter, abnormal gait, and mental retardation.



A. Anticipation
B. Genetic drift
C. Heteroplasmy
D. Imprinting
E. Pseudodominant inheritance

This question is part of NBME 13 Section 2 (50 questions)
Asked by Chachelly, Last updated: Mar 27, 2020

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Chachelly

Chachelly

Answered Jul 25, 2018

Imprinting
 

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