There are only three elements in two molecules of aspirin. If the formula for aspirin is C9H8O4, then there are nine carbon atoms, eight hydrogen atoms, and four oxygen atoms on every molecule of aspirin. It will not change from molecule to molecule. Therefore, there are only three elements in two molecules of aspirin: carbon, hydrogen, and oxygen.
This is a basic tenet of chemistry. Unless there is a reaction with something else, most molecules will not change on their own. So, to add a fourth element or to take away an element, one has to create a reaction. This means there has to be a catalyst of some kind, and something to react with the aspirin. An example would be in the stomach: hydrochloric acid reacts with the aspirin to break it down.
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