What is the most serious form of bone marrow toxicity?

Aplastic anemia.;

Oral contraceptives have been associated with an increased risk of stroke. myocardial infarction. and deep vein thrombosis. These risks are increased in women who smoke. Increased skin oil and acne are effects of progestin excess. Headache and dizziness are effects of estrogen excess. Early or mid-cycle bleeding are effects of estrogen deficiency.;