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Which of the following mediators is most likely causing this patients fever and leukocytosis? A 20-year-old man has cramping periumbilical pain. After several hours, the pain shifts to the right lower quadrant and becomes constant. His temperature is 40°C (104°F), and his leukocyte count is 20.000/mm³ with 90% neutrophils.



A. Interleukin-1 (IL-1)
B. Interleukin-2 (IL-2)
C. Leukotriene Bâ‚„
D. Leukotriene Câ‚„
E. Prostaglandin Dâ‚‚

This question is part of NBME 13 Section 4 (qst 1-50)
Asked by Chachelly, Last updated: Jun 28, 2020

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2 Answers

C. Bernthal

Its kind of my job to give answers

C. Bernthal, Teacher, MA, P.hD, Seattle

Answered May 29, 2019

Leukocytosis is a situation which affects the white cells in a person. Specifically, it means that the white blood cells are above the average amount in the bloodstream that someone should have. If someone has an infection or a body part is inflamed, then their white blood cell count may escalate as a result of that.

There are five types of ailment, including basophilia, eosinophilia, monocytosis, lymphocytosis, and neutrophilia. If a patient comes to the hospital and is complaining of a fever and leukocytosis, then the doctor may ask this man about his symptoms. He may be experiencing pain and cramping. His temperature is high. His leukocyte count is at 20.000/mm with 90% neutrophils. Therefore, this may be caused by Interleukin 1.

 

Chachelly

Chachelly

Answered Apr 05, 2018

Interleukin-1 (IL-1)
 

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