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A 70-year-old man comes to the physician because of a rash for 7 days. Physical examination shows multiple 4-to s-cm tense bullae filled with clear fluid over the inner aspects of the forearms, lower abdomen, groin, and thighs_ Examination of a skin biopsy specimen shows a non-acantholytic blister with separation of the epidermis from the basement membrane. Serologic studies are most likely to show an autoantibody directed against which of the following?



A. Anchoring filaments
B. Collagen, type IV
C. Desmosomal proteins
D. Hemidesmosomal proteins
E. Intracellular adhesion molecule-1

This question is part of NBME 13 Section 2 (50 questions)
Asked by Chachelly, Last updated: Mar 25, 2020

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Chachelly

Chachelly

Answered Mar 27, 2018

Hemidesmosomal proteins

This is Bullous pemphigoid
 

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