What do Regulatory CD4 T cells suppress? - ProProfs Discuss
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What do Regulatory CD4 T cells suppress?



A. CD4 self-reactive T cells
B. CD8 self-reactive T cells
C. AIRE gene mutation
D. RAG 1 gene
E. RAG 2 gene

This question is part of Immunology Exam (CH.5-7)
Asked by Lrswimmer, Last updated: Feb 11, 2020

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2 Answers

L. Cooper

Analyst by profession but writer by heart.

L. Cooper, Data Analyst, MCA, Newcastle

Answered Oct 03, 2019

The correct answer is option A – CD4 self-reactive T cells. Regulatory T cells also called Tregs are types of T cells that have a role in suppressing cells of the immune system. They help to control the response of the immune system to self and foreign antigen. Regulatory T cells help the body to be able to tell the self and non-self apart.

They also play an important role in preventing autoimmune diseases. In the case where there is a problem with the regulatory cells, autoimmune diseases may occur. Regulatory CD4 T cells ensure that CD 4 self-reactive T cells are suppressed. They produce substances such as Interleukin 10, adenosine and TGF beta which help in the suppression of immune cells. A mutation in the gene that codes for Foxp3 has been notated to cause a severe and rapid autoimmune disorder called immune dysfunction. Hope you find this information helpful.

 

lrswimmer

Lrswimmer

Answered Mar 11, 2018

CD4 self-reactive T cells
 

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