The Incan Empire was overthrown by Francisco Pizarro, who was a Spanish conquistador. The Spanish conquest of the Incan empire was an important campaign in the Spanish colonization of the Americas. The Spanish conquered the Incans after a victorious battle known as the Battle of Cajamarca in 1532. The Incan empire was the most significant pre-Columbian succession disputes between the ruling family.
Unrests in the newly conquered territory and the spread of chickenpox further weakened the Incan empire against external attacks. Disputes between the sons of the emperor triggered the Incan war giving the Spanish an upper hand in acquiring support from local leaders. The Spanish had superiority over the Incas regarding their military knowledge and tactics as well as support from native tribes who sought to end the rule of the Incan dynasty.