Which of the following adverse effects might most likely occur during - ProProfs
     

Which of the following adverse effects might most likely occur during the first days of therapy(of the patient in the case below)?
A 55-year-old man suffering from bipolar disorder started a therapy which included lithium, two tablets daily.



A. Constipation
B. Weight loss
C. Insomnia
D. Hypertension
E. Edema

This question is part of Block 13 Pharm Bipolar pharmacology

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1 Answer

John Smith

John Smith

Answered on Oct 07, 2016

1. Edema

Learning objective: describe the adverse effects of lithium. Answer: E Edema is a frequent adverse effect of Li+ especially during the 5-7 days of therapy. Edema is likely due to increased NA+ in the ECF, since Li+ is not pumped out by NA+/K+ ATPase and therefore it tends to accumulate inside the cells, displacing Na+. A, B, C, D) Actually Li+ causes adverse effects opposite to those listed.

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