Serology Unit 6.4 Viral Diseases

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SEROLOGY UNIT 6. 4 VIRAL DISEASES

  
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  • 1. 
    WHAT IS THE ENVELOPE MADE OF AND WHAT IS IT USED FOR

  • 2. 
    WHAT FIVE THINGS CAN CAUSE HEPATITIS

  • 3. 
    WHAT ARE THE SIX PRIMARY HEPATITIS VIRUSES

  • 4. 
    HOW IS HEPATITIS A VIRUS TRANSMITTED

  • 5. 
    WHEN IS HEPATITIS A IGM ANTIBODY DETECTABLE AND WHERE

  • 6. 
    WHEN IS HEPATITIS A IGG ANTIBODY DETECTED AND INDICATING WHAT

  • 7. 
    WHAT ARE THE TWO TESTS FOR HEPATITIS A, AND WHAT DO THEY TEST FOR

  • 8. 
    HOW IS HEP B SPREAD

  • 9. 
    CHRONIC INFECTION OF HEP B CAN LEAD TO

  • 10. 
    INCIDENCE OF TRANSFUSION ACQUIRED HBV REDUCED SINCE HIGH-RISK DONOR GROUPS HAVE BEEN ELIMINATED, WHAT ARE THEY

  • 11. 
    HCV IS CLINICALLY AND EPIDEMIOLOGICALLY SIMILAR TO HEPATITIS B.  HOW IS HCV TRANSMITTED AND WHO DOES IT EFFECT MOST

  • 12. 
    HCV OCCURES IN PRIMARILY IN DEVELOPED CONTRIES LIKE

  • 13. 
    HDV IN THE US IS MOSTLY SEEN IN

  • 14. 
    WHAT IS THE INTERPRETATION OF SIMULTANEOUS INFECTION (COINFECTIION)

  • 15. 
    WHAT IS THE INTERPRETATION OF HDV SUPERINFECTION

  • 16. 
    WHAT IS THE ONLY DIAGNOSTIC EVALUATION FOR HGV

  • 17. 
    WHAT ARE THE CLINICAL MANIFESTATIONS IN THE EARLY STAGES OF AIDS

  • 18. 
    WHAT ARE THE CLINICAL MANIFESTATIONS OF LATE PHASE IN AIDS

  • 19. 
    AFTER THE AIDS VIRUS BINDS TO CD4 WHAT HAPPENS NEXT

  • 20. 
    WHAT ARE THE 3 ANTIBODIES AGAINST AIDS

  • 21. 
    WHAT VIRUS MAY BE PRESENT IN BLOOD, URINE, AND BREAST MILK AND IS DNA BASED MEMBER OF HERPES FAMILY

  • 22. 
    HOW IS CMV TRANSMITTED

  • 23. 
    OBLIGATE INTRACELLULAR  PARASITE CONTAINS WHAT
    • A. 

      DNA OR RNA

    • B. 

      ENCELOPE

    • C. 

      CAPSID

    • D. 

      ICOSAHEDRAL


  • 24. 
    WHAT IS THE SIZE OF OBLIGATE PARASITES
    • A. 

      20-30 mm

    • B. 

      20-25 nm

    • C. 

      20-35 nm

    • D. 

      20-30 nm


  • 25. 
    REPRODUCTION TAKES PLACE BY _______ ___________

  • 26. 
    VIRION NEVER POSSESS BOTH _____ AND _____ TOGETHER

  • 27. 
    LACKS COMPONENTS NECESSARY FOR INDEPENDENT LIFE AND REPLICATION
    • A. 

      ENVELOPE

    • B. 

      INERT VIRION

    • C. 

      CAPSID

    • D. 

      DNA, RNA


  • 28. 
    THIS COMPONENT ENCASES THE GENOME, ASSEMBLED FORM IDENTICAL PROTEIN SUBUNITS, PROTECTS THE RNA/DNA ALLOWS THE VIRION TO ATTACH TO THE HOST CELLS, AND INITATES THE INFECTION
    • A. 

      ENCELOPE

    • B. 

      HELICAL

    • C. 

      NUCLEIC ACID

    • D. 

      CAPSID


  • 29. 
    ________ IS A ROD-LIKE CYLINDRICAL STRUCTURE

  • 30. 
    _______ IS GENERALLY SPHERICAL

  • 31. 
    ___________ GENERIC TERM REFERRING TO INFLAMMATION OF THE LIVER

  • 32. 
    WHAT ARE THE 4 FORMS OF HEPATITIS:  ________, ________, _________, AND_________

  • 33. 
    WHAT ARE THE 4 FORMS OF SECONDARY HEPATITIS:  __________, ___________, ________, AND ___________

  • 34. 
    WHAT IS A TYPICAL FORM OF JAUNDICE THAT NORMALY LASTS 6 MONTHS OR LESS
    • A. 

      ACUTE

    • B. 

      FULMINANT

    • C. 

      SUBCLINICAL

    • D. 

      CHRONIC


  • 35. 
    WHAT PHASE IS REFERRED TO AS THE INITIAL INFECTION
    • A. 

      INCUBATION

    • B. 

      PREICTERIC

    • C. 

      ICTERIC

    • D. 

      CONVALESCENCE


  • 36. 
    WHAT PHASE IS REFERRED TO AS PRIOR TO THE SIGNS AND SYMTOMS
    • A. 

      INCUBATION

    • B. 

      PREICTERIC

    • C. 

      ICTERIC

    • D. 

      CONVALESCENCE


  • 37. 
    WHAT PHASE IS REFERRED TO AS ACTUAL PHASE OF ILLNESS
    • A. 

      INCUBATION

    • B. 

      PREICTERIC

    • C. 

      ICTERIC

    • D. 

      CONVALESCENCE


  • 38. 
    WHAT PHASE IS REFERRED TO AS THE "RECOVERY" PHASE, BUT IS STILL INFECTIOUS
    • A. 

      INCUBATION

    • B. 

      PREICTERIC

    • C. 

      ICTERIC

    • D. 

      CONCALESCENCE


  • 39. 
    WHAT IS A RARE FORM OF HEPATITIS THAT IS ASSOCIATED WITH HEPATIC FAILURE (POTENTIALLY FATAL)
    • A. 

      ACUTE

    • B. 

      FULMINANT

    • C. 

      SUBCLINICAL

    • D. 

      CHRONIC


  • 40. 
    WHAT FORM OF HEPATITIS IS WITHOUT JAUNDICE OR CARRIER STATE (ASYMPTOMATIC) AND ACCOUNTS FOR PERSONS WITH DEMONSTRABLE ANTIBODIES BUT NO HISTORY OF HEPATITIS
    • A. 

      ACUTE

    • B. 

      FULMINANT

    • C. 

      SUBCLINICAL

    • D. 

      CHRONIC


  • 41. 
    FORM OF HEPATITIS THAT IS HEPATIC INFLAMMATION AND NECROSIS LASTING LONGER THAN 6 MONTHS, AND OCCURS IN ABOUT 10% OF HEPATITIS B PATIENTS
    • A. 

      ACUTE

    • B. 

      FULMINANT

    • C. 

      SUBCLINICAL

    • D. 

      CHRONIC


  • 42. 
    __________ __ FORM OF HEPATITIS FORMERLY CALLED INFECTIOUS HEPATITIS OR SHORT INCUBATION HEPATITIS

  • 43. 
    TRUE OR FALSE. CARRIER STATE AND CHRONIC HEPATITIS DO NOT OCCUR IN HEPATITIS A VIRUSES

  • 44. 
    HEPATITIS _____ VIRUS IS DETECTED IN STOOL ONLY

  • 45. 
    WHAT IS THE INCUBATION PERIOD FOR HEPATITIS A VIRUS
    • A. 

      15-45 AND AN AVERAGE OF 28

    • B. 

      45-180 AND AN AVERAGE OF 120

    • C. 

      15-150

    • D. 

      30-50


  • 46. 
    HEPATITIS _____ IS FORMERLY CALLED AUSTRALIAN ANTIGEN AND SERUM HEPATITIS

  • 47. 
    WHAT IS THE INCUBATION TIME OF HEP B
    • A. 

      15-45 AVRAGE OF 28

    • B. 

      45-180 AVRAGE OF 120

    • C. 

      15-150

    • D. 

      30-50

    • E. 

      2-4


  • 48. 
    THE HBV IS A DOUBLE SHELLED PARTICLE-_________ _________, WITH A DOUBLE ___________ _____

  • 49. 
    WHAT IS THE HBV SURFACE ANTIGEN
    • A. 

      HBsAg

    • B. 

      HBeAg

    • C. 

      HBcAb

    • D. 

      HBsAb

    • E. 

      HBeAb


  • 50. 
    ____________ IS THE OUTER MOST COAT AND IS THE FIRST DETECTABLE MARKER IN SERUM DURING INCUBATION PERIOD OF HEP B

  • 51. 
    FIRST DETECTABLE MARKER IN SERUM 1-5 MONTHS AFTER EXPOSURE, PEAKING AT 3 MONTHS, ______________ INDACATES THAT THE PATIENT IS INFECTIOUS

  • 52. 
    ____________ IS DETECTED IN SOME HBsAg POSITIVE PEOPLE, RARELY IN HBsAg NEGATIVE PEOPLE, AND IS CLOSELY ASSOCIATED WITH THE HBV CORE BUT RELATIONSHIP UNCLEAR BETWEEN HBe AND HBV

  • 53. 
    THE ______________ IS A RELIABLE MARKER FOR THE PRESENCE OF HIGH LEVELS OF VIRUS AND DEGREE OF INFECTIVITY

  • 54. 
    ____________ IS DETECTABLE AT 2 MONTHS AND INDICATES CURRENT OR ___________ INFECTION

  • 55. 
    _____________ DEVELOP DURING CONVALESCENCE AND RECOVERY._____________ IS A SEROLOGICAL MARKER FOR RECOVERY AND IMMUNITY

  • 56. 
    ____________ IN ACUTE HEPATITIS INDICATES INFECTION IS BEING RESOLBED

  • 57. 
    ___________ IS THE MOST POPULAR METHOD FOR DETECTING HEPATITIS B ANTIGENS AND ANTIBODIES

  • 58. 
    ______________ OF PATIENTS EXPOSED TO HCV WILL DEVELOP CHRONIC HEPATITIS

  • 59. 
    WHAT IS THE INCUBATION PERIOD OF HEPATITIS C VIRUS
    • A. 

      15-45

    • B. 

      45-180

    • C. 

      15-150

    • D. 

      30-50


  • 60. 
    THE TREATMENT FOR THIS HEPATITIS IS TO ELIMINATE THE DETECTABLE VIRAL RNA FROM BLOOD
    • A. 

      HEP B

    • B. 

      HEP C

    • C. 

      HDV

    • D. 

      HEP A


  • 61. 
    THIS HEPATITIS REQUIRES HBV AS A HELPER BECAUSE THE VIRUS IS DEFECTIVE, PEOPLE WHO ARE HBsAG POSITIVE CAN BE INFECTED BY THIS HEPATITIS AND IS COMMON IN ITALY AND S. EUROPEAN COUNTRIES
    • A. 

      HEP B

    • B. 

      HEP C

    • C. 

      HDV

    • D. 

      HEP A


  • 62. 
    FIRST DESCRIBED AS PATHOGEN WHICH ________________ SOME PATIENTS WHO ARE ALREADY INFECTED WITH HBV

  • 63. 
    IN THIS HEPATITIS; FULMINANT AND CHRONIC HEPATITIS IS ATTRIBUTED FOR BEING FREQUENT WITH AN INCUBATION TIME OF 30-50 DAYS AND ALSO APPEARS TO BE ENDEMIC AMONG INDIAN TRIBES LIVING IN THE AMAZON RIVER
    • A. 

      HEP B

    • B. 

      HEP C

    • C. 

      HDV

    • D. 

      HEP A


  • 64. 
    HD ANTIGEN IS DETECTED IN THE ___________

  • 65. 
    ANTI-DELTA (ANTIBODY DELTA) IS DETECTABLE IN ___________

  • 66. 
    SIMILAR TO HEP A VIRUS, TRANSMITTED THROUGH FECAL-ORAL ROUTE, PRIMARILY FOUND IN DEVELOPING COUNTRIES, AND CHRONIC STATE DOES NOT EXSIST
    • A. 

      HEP B

    • B. 

      HEV

    • C. 

      HVD

    • D. 

      HEP C


  • 67. 
    IN HEV; FULMINANT HEPATITIS IS FOUND IN __________% OF PREGNANT WOMEN

  • 68. 
    THIS HEPATITIS CAN BE DETECTED IN STOOL SPOECIMEN BY IMMUNOELECTRON MICROSCOPY
    • A. 

      HEV

    • B. 

      HEP B

    • C. 

      HEP A

    • D. 

      HEP C


  • 69. 
    THIS HEPATITIS RNA VIRUS IS CLOSELY RELATED TO HCV, IS A SEXUALLY TRANSMITTED BLOOD BORNE AGENT THAT FREQUENTLY OCCURES A COINFECTION WITH HCV, TRANSFUSION RECIPENTS AND IV DRUG ABUSERS ARE AT RISK
    • A. 

      HVD

    • B. 

      HEV

    • C. 

      HEP C

    • D. 

      HGV


  • 70. 
    IMMUNE DISORDER WHICH AFFECTS T-LYPHS, TRANSMITS THROUGH EXCHANGE OF BODY FLUID, INTIMATE CONTACT WITH BLOOD FROM INFECTED PERSON, AND DRUG PARAPHERNALIA, TRANSFUSION OF BLOOD PRODUCTS AND TRANSPLACENTALLY
    • A. 

      CMV

    • B. 

      AIDS

    • C. 

      HSV

    • D. 

      RUBELLA


  • 71. 
    HIV IS A RETROVIRUS TRO THIS DISEASE PROCESS AND A MAJOR TARGET OF THE VIRUS IS THE T-HELPER CELLS
    • A. 

      RUBELLA

    • B. 

      AIDS

    • C. 

      HIV

    • D. 

      CMV


  • 72. 
    ONLY ______, ___________, _____________ AND _______ ___________ HAVE BEEN IMPLICATED IN TRANSMISSION

  • 73. 
    SINGLE STRAND RNA, REVERSE TRANSCRIPTASE ENZYME WHICH CONVERTS RNA INTO DNA
    • A. 

      CD4

    • B. 

      CORE SHELL

    • C. 

      OUTER ENVELOPE

    • D. 

      RETROVIRUS


  • 74. 
    PHOSPHOLIPID BILAYERS, HUMAN LEUKOCYTE ANTIGEN, GLYCOPROTEINS; 41 & 120
    • A. 

      CD4

    • B. 

      CORE SHELL

    • C. 

      OUTER ENVELOPE

    • D. 

      RETROVIRUS


  • 75. 
    CONTAINS PROTEINS 24 AND 19
    • A. 

      CD4

    • B. 

      CORE SHELL

    • C. 

      OUTER ENVELOPE

    • D. 

      RETROVIRUS


  • 76. 
    VIRUS BINDS TO _______ RECEPTORS ON TARGET CELLS SUCH AS; HELPER-INDUCER T-LYMPHS, MONOCYTES-MACROPHAGES, ______ _________, AND B LYMPHS

  • 77. 
    CAUSATIVE AGENT OF AIDS IN US AND EUROPE
    • A. 

      HIV-3

    • B. 

      HIV-1

    • C. 

      HIV-2

    • D. 

      HIV-0


  • 78. 
    ASSOCIATED WITH IMMUNODEFICIENCY SIMILAR TO AIDS IN WEST AFRICA
    • A. 

      HIV-3

    • B. 

      HIV-1

    • C. 

      HIV-2

    • D. 

      HIV-0


  • 79. 
    ______ MOST WIDELY USED FOR SCREENING IN AIDS AND COLOR CHANGE IS PROPORTIONAL TO AMOUNT OF ANTIBODY PRESENT

  • 80. 
    CONFIRMATORY TEST TO AIDS IN WHICH HIV PROTEINS ARE SEPERATED BY ELECTROPHORESIS AND TRANSFERED TO NITROCELLULOSE SHEETS AND CUT INTO STRIPS
    • A. 

      RIA

    • B. 

      EIA

    • C. 

      IMMUNOFLORESCENCE

    • D. 

      WESTERN BLOT


  • 81. 
    LINKED TO ADULT T-CELL LUKEMIA AND TRANSMITTED BY TRANSFER OF INFECTED CELLS
    • A. 

      HTLV-2

    • B. 

      HIV-1

    • C. 

      HTLV-1

    • D. 

      HIV-2


  • 82. 
    LINKED TO HAIRY CELL LUKEMIA
    • A. 

      HTLV-2

    • B. 

      HIV-1

    • C. 

      HTLV-1

    • D. 

      HIV-2


  • 83. 
    OCASSIONAL SELF-LIMITED, HETEROPHILE NEGATIVE, AND MONONUCLEOSIS SYMPTOMS. BY ADULTHOOD MOST INDIVIDUALS HAVE EXPERIENCED ASYMPTOMATIC SYMPTOMS
    • A. 

      AQUIRED CMV

    • B. 

      CONGENITAL CMV


  • 84. 
    ONE OF THE MOST IMPORTANT CAUSES OF VIRAL INFECTIONS IN THE US WITH RETINITIS AS A SYMPTOM
    • A. 

      AQUIRED CMV

    • B. 

      CONGENITAL CMV


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