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Patho Chapter 5

23 Questions
Pathology Quizzes & Trivia

Patho. Chapter. Five.

Questions and Answers
  • 1. 
    What is a benign neoplasm originating from adipose tissue called?
    • A. 

      Adenoma

    • B. 

      Lipoma

    • C. 

      Fibrosarcoma

    • D. 

      Adenocarcinoma

  • 2. 
    What are malignant neoplasms arising from connective tissue cells called?
    • A. 

      Carcinomas

    • B. 

      Sarcomas

    • C. 

      Melanomas

    • D. 

      Fibromas

  • 3. 
    Which of the following is a characteristic of a benign tumor?
    • A. 

      Unencapsulated, invasive

    • B. 

      It consists of undifferentiated cells

    • C. 

      It exerts systemic effects

    • D. 

      Cells appear relatively normal

  • 4. 
    What is the grading of newly diagnosed malignant tumors based on?
    • A. 

      Size of the tumor

    • B. 

      Number of metastases

    • C. 

      Degree of differentiation of the cells

    • D. 

      Number of lymph nodes involved

  • 5. 
    A warning sign of possible cancer would be any of the following except:
    • A. 

      Persistent, unusual bleeding

    • B. 

      A change in bowel habits

    • C. 

      Sudden development of fever, nausea, and diarrhea

    • D. 

      A change in shape, color, or surface of a skin lesion

  • 6. 
    The common local effects of an expanding tumor mass include 1. obstruction of a tube or duct 2. anemia and weight loss 3. cell necrosis and ulceration 4. tumor markers in the circulation
    • A. 

      1, 2

    • B. 

      1, 3

    • C. 

      2, 4

    • D. 

      3, 4

  • 7. 
    What does paraneoplastic syndrome refer to?
    • A. 

      The effects of substances such as hormones secreted by the tumor cells

    • B. 

      Severe weight loss and cachexia associated with advanced cancer

    • C. 

      The decreased resistance to infection resulting from malignant tumors

    • D. 

      The effects of multiple metastatic tumors

  • 8. 
    What is the spread of malignant cells through blood and lymph to distant sites called?
    • A. 

      Invasiveness

    • B. 

      Seeding

    • C. 

      Metastasis

    • D. 

      Systemic effect

  • 9. 
    One reason for staging a malignant tumor at the time of diagnosis is to:
    • A. 

      Identify the original cell from which the tumor developed

    • B. 

      Locate and identify the primary tumor

    • C. 

      Decide the initiating factor for a particular tumor

    • D. 

      Determine the best treatment and the prognosis

  • 10. 
    The process of carcinogenesis usually begins with:
    • A. 

      Exposure to promoters causing dysplasia

    • B. 

      Development of defective genes

    • C. 

      An irreversible change in the cell DNA

    • D. 

      A single exposure to a known risk factor causing temporary cell damage

  • 11. 
    What would be an external source of ionizing radiation?
    • A. 

      A needle containing a radioisotope implanted beside the tumor

    • B. 

      Gamma rays delivered by a cobalt machine

    • C. 

      A dose of a radioactive drug to be ingested

    • D. 

      A fluid containing radioactive material instilled in a body cavity

  • 12. 
    Radiation therapy destroys:
    • A. 

      All cells in the tumor at one time

    • B. 

      The cells in the center of the tumor

    • C. 

      Primarily rapidly dividing cells

    • D. 

      Radioresistant cells

  • 13. 
    The most critical adverse effects of chemotherapy and radiation therapy include:
    • A. 

      Thrombocytopenia and leukopenia

    • B. 

      Headache and lethargy

    • C. 

      Nausea and constipation

    • D. 

      Alopecia and weight loss

  • 14. 
    Chemotherapy usually involves a combination of drugs in order to: 1. reduce the adverse effects 2. guarantee that all cancer cells are destroyed 3. be effective in more phases of the cell cycle 4. totally block the mitotic stage
    • A. 

      1, 3

    • B. 

      1, 4

    • C. 

      2, 3

    • D. 

      3, 4

  • 15. 
    Why does ovarian cancer have a poor prognosis?
    • A. 

      The ovaries are inaccessible

    • B. 

      Specific signs rarely appear until after secondary tumors develop

    • C. 

      The same tumor markers are present with many types of cancer

    • D. 

      No effective treatment is available

  • 16. 
    Select the correct pair representing a malignant tumor and its marker:
    • A. 

      Colon cancer: carcinoembryonic antigen (CEA)

    • B. 

      Hepatic cancer: CA125

    • C. 

      Prostate cancer: human chorionic gonadotropin (HCG)

    • D. 

      Testicular cancer: Philadelphia chromosome

  • 17. 
    Anti-angiogenesis drugs act on malignant tumor by:
    • A. 

      Promoting the immune response and removal of tumor cells

    • B. 

      Blocking hormonal stimulation of tumor cells

    • C. 

      Reduce blood flow and nutrient supply to tumor cells

    • D. 

      Transport radioisotopes into tumor to destroy cells

  • 18. 
    The development of neutropenia during chemotherapy for cancer means:
    • A. 

      The cancer cells are being destroyed quickly

    • B. 

      The patient is likely to hemorrhage

    • C. 

      Higher doses of chemotherapy could be tolerated by this patient

    • D. 

      The patient is at high risk for infection

  • 19. 
    Malignant brain tumors:
    • A. 

      Metastasize quickly to all parts of the body

    • B. 

      Spread first to lungs and bone

    • C. 

      Spread to other parts of CNS

    • D. 

      Do not metastasize anywhere at any time

  • 20. 
    Identify the common dose-limiting factor for chemotherapy:
    • A. 

      Alopecia

    • B. 

      Bone marrow depression

    • C. 

      Nausea and vomiting

    • D. 

      Weight loss

  • 21. 
    Glucocorticoids are often prescribed during a course of chemotherapy and radiation because:
    • A. 

      Glucocorticoids greatly potentiate the effect of chemotherapy

    • B. 

      The immune system is stimulated

    • C. 

      Bone marrow is more active

    • D. 

      Inflammation around the tumor may be reduced

  • 22. 
    Vomiting frequently follows a chemotherapy treatment because: 1. the gastrointestinal tract is inflamed 2. the chemicals stimulate the emetic centre 3. the drugs have an unpleasant odor 4. treatment is very painful
    • A. 

      1 only

    • B. 

      1, 2

    • C. 

      2, 3

    • D. 

      2, 3, 4

  • 23. 
    What type of cells tend to be damaged the most during chemotherapy and radiation treatments?
    • A. 

      Epithelial cells

    • B. 

      Skeletal muscle cells

    • C. 

      Nerve tissue

    • D. 

      Collagen and fibrous tissue

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