Mic 541 Exam 4 - Mycology I And II

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MIC 541 Exam 4 - Mycology I and II

  
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1.  This drug is good for fungal meningitis since it can enter the CNS.
A.
B.
C.
D.
E.
2.  Fungi that infect only infect compromised hosts are clasified as?
A.
B.
C.
D.
E.
3.  Cutaneous Mycoses are also called Called tineas or ringworms
A.
B.
4.  Which of the following are true about treatment of tinea corporis?
A.
B.
C.
D.
E.
5.  Which of the following are true about Pityriasis Versicolor?
A.
B.
C.
D.
E.
6.  Which of the following are characteristic of terbinafine?
A.
B.
C.
D.
7.  Tinea pedis is the most prevalent dermatophytosis in U.S.
A.
B.
8.  Cryptococcosis may mimic brain tumor, abscess, or MS
A.
B.
9.  Fungi that infect outside layers of skin or hair only are classified as?
A.
B.
C.
D.
E.
10.  Which drug do fungi take it up using a permease that our cells do not make.  It gets incorporated into the fungal RNA in place of uracil. 
A.
B.
C.
D.
E.
11.   Histoplasmosis is the hallmark infection of AIDS patients
A.
B.
12.  Amphotericin causes the cell to be leaky, which alters its permeability to which of the following?
A.
B.
C.
D.
13.  Fluconazole is used to treat meningitis, because it can attain good CNS levels
A.
B.
14.  Which of the following is true regarding Cryptococcosis Treatment
A.
B.
C.
D.
E.
15.  Which antifungal drug can have the following side effects?males – may develop breastsfemales – irregular menstrual cyclesliver toxicity
A.
B.
C.
D.
E.
16.  Fungi are a main cause of human infection.
A.
B.
17.  Which antifungal drug inhibits cytochromes (cytochrome P450)?  This prevents ergosterol formation, which disrupts membrane function and growth
A.
B.
C.
D.
E.
18.  Nystatin is a polyene similar to Amphotericin B.
A.
B.
19.  Which of the following is not true regarding Histoplasma capsulatum
A.
B.
C.
D.
E.
20.  Which of the following is the cause of sporotrichosis?
A.
B.
C.
D.
21.  Which 3 genera are known as Dermatophytes
A.
B.
C.
D.
E.
22.  Fungi that are localized and enter by trauma are classified as?
A.
B.
C.
D.
E.
23.  Which of the following are Imidazoles that  are used as–topical replacements for nystatin 
A.
B.
C.
D.
24.  Thiazoles have the same SE but are less toxic than imidazoles
A.
B.
25.  Which of the following shows up as typical “ringworm” lesions
A.
B.
C.
D.
26.  Fungi that invade skin, hair, nails are classified as?
A.
B.
C.
D.
E.
27.  Echinocandins is a class of antifungals that act as a fungicidal for Candida and also work against Aspergillus
A.
B.
28.  Which of the following is not dimorphic and is the only medically important encapsulated yeast?
A.
B.
C.
29.  Fungi that are more virulent and cause disease in healthy hosts are classified as?
A.
B.
C.
D.
E.
30.  Which of the following is NOT true regarding treatment of tinea capitis?
A.
B.
C.
D.
E.
31.  The fungal cells can develop a resistance to *this drug* if given by itself, so it is usually given in combination with Amphotericin B
A.
B.
C.
D.
32.  A diaper rash is also known as a candidiasis infection.
A.
B.
33.  Which systemic mycosis is usually found in the oil of southwest U.S., Mexico, South America and is referred to as San Joaquin Valley Fever?
A.
B.
C.
D.
34.  A person can only get a certain amount of Amphotercin in his/her lifetime.
A.
B.
35.  Which of the following is a subcutaneous Mycosis known as “rose-handler’s” disease
A.
B.
C.
D.
36.  Which of the following is  mostly seen in children before puberty?
A.
B.
C.
D.
37.  Fungi reproduce by which fo the following?
A.
B.
C.
D.
38.  Which antifungal drug Blocks squalene epoxidase enzyme to prevent squalene conversion to ergosterol. 
A.
B.
C.
D.
E.
39.  Which antifungal drug binds to ergosterol in the fungal membrane and forms pores in the membrane?
A.
B.
C.
D.
E.
40.  Treat Sporotrichosis caused by  Sporothrix schenckii  with newer azole, e.g. itraconazole
A.
B.
41.  Which antifungal drug Inhibits β-(1,3)-D-glucan synthesis, which usually makes the cross-bridges in the fungal cell wall.  Therefore cell wall formation is inhibited
A.
B.
C.
D.
E.
42.  What is the primary focus of infection for Systemic Mycoses
A.
B.
C.
D.
43.  Infections from fungi occur mostly due to:
A.
B.
C.
D.
44.  Which of the following are not correctly matched?
A.
B.
C.
D.
E.
F.
45.  Which part of the fungal cell should a drug target so as to cause the least amount of damage to the human host?
A.
B.
C.
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