Related Topics
Take Another Quiz

Mic 541 Exam 4 - Mycology I And II

45 Questions
Biology Quizzes & Trivia

MIC 541 Exam 4 - Mycology I and II

Questions and Answers
  • 1. 
    Fungi are a main cause of human infection.
    • A. 

      True

    • B. 

      False

  • 2. 
    Infections from fungi occur mostly due to:
    • A. 

      Disruption of natural barriers

    • B. 

      Immunosuppression

    • C. 

      Occupational contact

    • D. 

      All of the above

  • 3. 
    • A. 

      Fission, as in bacteria

    • B. 

      Budding – mostly in yeasts

    • C. 

      Fragmentation of hyphae

    • D. 

      Spore formation by mold forms

  • 4. 
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 5. 
    Fungi that invade skin, hair, nails are classified as?
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 6. 
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 7. 
    Fungi that are more virulent and cause disease in healthy hosts are classified as?
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 8. 
    Fungi that infect only infect compromised hosts are clasified as?
    • A. 

      Superficial

    • B. 

      Cutaneous

    • C. 

      Subcutaneous

    • D. 

      Systemic

    • E. 

      Opportunistic

  • 9. 
    • A. 

      Cholesterol in cell membrane

    • B. 

      Ergosterol in cell membrane

    • C. 

      Nucleus

  • 10. 
    Which antifungal drug binds to ergosterol in the fungal membrane and forms pores in the membrane?
    • A. 

      Amphotericin

    • B. 

      5-fluorocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Caspofungin

  • 11. 
    • A. 

      Mg

    • B. 

      Na

    • C. 

      Cl

    • D. 

      K

  • 12. 
    • A. 

      True

    • B. 

      False

  • 13. 
    Which drug do fungi take it up using a permease that our cells do not make.  It gets incorporated into the fungal RNA in place of uracil. 
    • A. 

      Amphotericin

    • B. 

      5-fluorocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Caspofungin

  • 14. 
    The fungal cells can develop a resistance to *this drug* if given by itself, so it is usually given in combination with Amphotericin B
    • A. 

      5-fluorocytosine

    • B. 

      Terbinafine

    • C. 

      The azoles

    • D. 

      Capsofungin

  • 15. 
    This drug is good for fungal meningitis since it can enter the CNS.
    • A. 

      Amphotericin

    • B. 

      5-fluorocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Capsofungin

  • 16. 
    Which antifungal drug Blocks squalene epoxidase enzyme to prevent squalene conversion to ergosterol. 
    • A. 

      Amphotericin

    • B. 

      5-flurocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Capsofungin

  • 17. 
    • A. 

      Given orally

    • B. 

      Given topically

    • C. 

      Used to treat dermatophytes

    • D. 

      Used to treat nail infections

  • 18. 
    Which antifungal drug inhibits cytochromes (cytochrome P450)?  This prevents ergosterol formation, which disrupts membrane function and growth
    • A. 

      Amphotericin

    • B. 

      5-flurocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Capsofungin

  • 19. 
    Which antifungal drug can have the following side effects?males – may develop breastsfemales – irregular menstrual cyclesliver toxicity
    • A. 

      Amphotericin

    • B. 

      5-flurocytosine

    • C. 

      Terbinafine

    • D. 

      The azoles

    • E. 

      Capsofungin

  • 20. 
    Thiazoles have the same SE but are less toxic than imidazoles
    • A. 

      True

    • B. 

      False

  • 21. 
    Which antifungal drug Inhibits β-(1,3)-D-glucan synthesis, which usually makes the cross-bridges in the fungal cell wall.  Therefore cell wall formation is inhibited
    • A. 

      Amphotericin

    • B. 

      5-flurocytosine

    • C. 

      The azoles

    • D. 

      Terbinafine

    • E. 

      Capsofungin

  • 22. 
    • A. 

      Ketoconazole

    • B. 

      Clotrimazole

    • C. 

      Miconazole

    • D. 

      Voriconazole

  • 23. 
    Fluconazole is used to treat meningitis, because it can attain good CNS levels
    • A. 

      True

    • B. 

      False

  • 24. 
    • A. 

      True

    • B. 

      False

  • 25. 
    Nystatin is a polyene similar to Amphotericin B.
    • A. 

      True

    • B. 

      False

  • 26. 
    • A. 

      Chronic infection

    • B. 

      Superficial infection of outer skin

    • C. 

      Hypo- or hyperpigmented scaly lesions

    • D. 

      Can be treated by keratinolytic agents (salicylic acid)

    • E. 

      Can be treated by topical imidazoles (miconazole)

  • 27. 
    • A. 

      Sporothrix sp

    • B. 

      Microsporum sp.

    • C. 

      Trichophyton sp.

    • D. 

      Epidermophyton sp

    • E. 

      Histoplasma sp.

  • 28. 
    Cutaneous Mycoses are also called Called tineas or ringworms
    • A. 

      True

    • B. 

      False

  • 29. 
    Which of the following are not correctly matched?
    • A. 

      Tinea corporis – hairy body parts

    • B. 

      Tinea capitis – scalp

    • C. 

      Tinea pedis – athlete’s foot

    • D. 

      Tinea barbae – beard

    • E. 

      Tinea cruris – jock itch

    • F. 

      Tinea unguium – jock itch

  • 30. 
    Which of the following shows up as typical “ringworm” lesions
    • A. 

      Tinea corporis

    • B. 

      Tinea capitis

    • C. 

      Tinea cruris

    • D. 

      Tinea unguium

  • 31. 
    • A. 

      Topical treatment usually lasts 2-4 monthhs

    • B. 

      Miconazole is used topically

    • C. 

      Clotrimazole is used topically

    • D. 

      Treatment can be stopped as soon as clearing is noted

    • E. 

      Itraconazole and terbinafine can be used orally as needed

  • 32. 
    • A. 

      Tinea corporis

    • B. 

      Tinea unguium

    • C. 

      Tinea cruris

    • D. 

      Tinea capitis

  • 33. 
    Which of the following is NOT true regarding treatment of tinea capitis?
    • A. 

      Only topical treatment is needed

    • B. 

      1-2 months

    • C. 

      Terbinafine cream

    • D. 

      Shampoo frequently with selinium sulfide

    • E. 

      Topical azoles

  • 34. 
    Tinea pedis is the most prevalent dermatophytosis in U.S.
    • A. 

      True

    • B. 

      False

  • 35. 
    • A. 

      Cryptocococcosis

    • B. 

      Histoplasmosis

    • C. 

      Sporotrichosis

    • D. 

      Tinea cruris

  • 36. 
    • A. 

      Coccidioides immitis

    • B. 

      Sporothrix schenckii

    • C. 

      Cryptococcus neoformans

    • D. 

      Histoplasma capsulatum

  • 37. 
    Treat Sporotrichosis caused by  Sporothrix schenckii  with newer azole, e.g. itraconazole
    • A. 

      True

    • B. 

      False

  • 38. 
    • A. 

      Lung

    • B. 

      Heart

    • C. 

      Skin

    • D. 

      Liver

  • 39. 
    Which systemic mycosis is usually found in the oil of southwest U.S., Mexico, South America and is referred to as San Joaquin Valley Fever?
    • A. 

      Histoplasmosis

    • B. 

      Coccidioidomycosis

    • C. 

      Cryptocococcosis

    • D. 

      Blastomycosis

  • 40. 
    Which of the following is not true regarding Histoplasma capsulatum
    • A. 

      Most cases are in mid-western U.S.

    • B. 

      It is capsulated

    • C. 

      80% of people in Ohio, Mississippi River Valleys skin test positive

    • D. 

      Is the cause of Histoplasmosis

    • E. 

      Growth in soil stimulated by bird, bat dung

  • 41. 
    Which of the following is not dimorphic and is the only medically important encapsulated yeast?
    • A. 

      Histoplasma capsulatum

    • B. 

      Cryptococcus neoformans

    • C. 

      Coccidioides immitis

  • 42. 
    • A. 

      True

    • B. 

      False

  • 43. 
    Cryptococcosis may mimic brain tumor, abscess, or MS
    • A. 

      True

    • B. 

      False

  • 44. 
    • A. 

      Not usually needed for pulmonary infection

    • B. 

      Mandatory for meningitis

    • C. 

      Amphotericin B i.v. ± 5-flurocytosine

    • D. 

      Sometimes can switch to oral azole

    • E. 

      All of the above are true

  • 45. 
    • A. 

      True

    • B. 

      False

Related Topics