Mic 541 Exam 4 - Mycology I And II

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MIC 541 Exam 4 - Mycology I and II

  
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1.  Thiazoles have the same SE but are less toxic than imidazoles
A.
B.
2.  Treat Sporotrichosis caused by  Sporothrix schenckii  with newer azole, e.g. itraconazole
A.
B.
3.  The fungal cells can develop a resistance to *this drug* if given by itself, so it is usually given in combination with Amphotericin B
A.
B.
C.
D.
4.  Which of the following shows up as typical “ringworm” lesions
A.
B.
C.
D.
5.  Infections from fungi occur mostly due to:
A.
B.
C.
D.
6.  Fungi that are localized and enter by trauma are classified as?
A.
B.
C.
D.
E.
7.  Fungi reproduce by which fo the following?
A.
B.
C.
D.
8.  Amphotericin causes the cell to be leaky, which alters its permeability to which of the following?
A.
B.
C.
D.
9.  This drug is good for fungal meningitis since it can enter the CNS.
A.
B.
C.
D.
E.
10.  Which antifungal drug Blocks squalene epoxidase enzyme to prevent squalene conversion to ergosterol. 
A.
B.
C.
D.
E.
11.  Fungi that infect only infect compromised hosts are clasified as?
A.
B.
C.
D.
E.
12.  A diaper rash is also known as a candidiasis infection.
A.
B.
13.  Which of the following is not true regarding Histoplasma capsulatum
A.
B.
C.
D.
E.
14.  Which antifungal drug inhibits cytochromes (cytochrome P450)?  This prevents ergosterol formation, which disrupts membrane function and growth
A.
B.
C.
D.
E.
15.  Which part of the fungal cell should a drug target so as to cause the least amount of damage to the human host?
A.
B.
C.
16.  Which of the following are true about treatment of tinea corporis?
A.
B.
C.
D.
E.
17.  Which drug do fungi take it up using a permease that our cells do not make.  It gets incorporated into the fungal RNA in place of uracil. 
A.
B.
C.
D.
E.
18.   Histoplasmosis is the hallmark infection of AIDS patients
A.
B.
19.  Which systemic mycosis is usually found in the oil of southwest U.S., Mexico, South America and is referred to as San Joaquin Valley Fever?
A.
B.
C.
D.
20.  Fungi that infect outside layers of skin or hair only are classified as?
A.
B.
C.
D.
E.
21.  Which of the following is a subcutaneous Mycosis known as “rose-handler’s” disease
A.
B.
C.
D.
22.  Which of the following is not dimorphic and is the only medically important encapsulated yeast?
A.
B.
C.
23.  Which of the following is the cause of sporotrichosis?
A.
B.
C.
D.
24.  Cutaneous Mycoses are also called Called tineas or ringworms
A.
B.
25.  Fungi are a main cause of human infection.
A.
B.
26.  Which of the following are Imidazoles that  are used as–topical replacements for nystatin 
A.
B.
C.
D.
27.  Nystatin is a polyene similar to Amphotericin B.
A.
B.
28.  Which of the following is  mostly seen in children before puberty?
A.
B.
C.
D.
29.  Cryptococcosis may mimic brain tumor, abscess, or MS
A.
B.
30.  A person can only get a certain amount of Amphotercin in his/her lifetime.
A.
B.
31.  Tinea pedis is the most prevalent dermatophytosis in U.S.
A.
B.
32.  Which of the following are characteristic of terbinafine?
A.
B.
C.
D.
33.  Fluconazole is used to treat meningitis, because it can attain good CNS levels
A.
B.
34.  Fungi that invade skin, hair, nails are classified as?
A.
B.
C.
D.
E.
35.  Which of the following are not correctly matched?
A.
B.
C.
D.
E.
F.
36.  Echinocandins is a class of antifungals that act as a fungicidal for Candida and also work against Aspergillus
A.
B.
37.  Which of the following are true about Pityriasis Versicolor?
A.
B.
C.
D.
E.
38.  Which antifungal drug Inhibits β-(1,3)-D-glucan synthesis, which usually makes the cross-bridges in the fungal cell wall.  Therefore cell wall formation is inhibited
A.
B.
C.
D.
E.
39.  Fungi that are more virulent and cause disease in healthy hosts are classified as?
A.
B.
C.
D.
E.
40.  Which antifungal drug can have the following side effects?males – may develop breastsfemales – irregular menstrual cyclesliver toxicity
A.
B.
C.
D.
E.
41.  Which of the following is true regarding Cryptococcosis Treatment
A.
B.
C.
D.
E.
42.  Which antifungal drug binds to ergosterol in the fungal membrane and forms pores in the membrane?
A.
B.
C.
D.
E.
43.  Which of the following is NOT true regarding treatment of tinea capitis?
A.
B.
C.
D.
E.
44.  What is the primary focus of infection for Systemic Mycoses
A.
B.
C.
D.
45.  Which 3 genera are known as Dermatophytes
A.
B.
C.
D.
E.
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