Mic 541 Exam 4 - Mycology I And II

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MIC 541 Exam 4 - Mycology I and II

  
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1.  Fungi are a main cause of human infection.
A.
B.
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2.  Infections from fungi occur mostly due to:
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B.
C.
D.
3.  Fungi reproduce by which fo the following?
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B.
C.
D.
4.  Fungi that infect outside layers of skin or hair only are classified as?
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B.
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D.
E.
5.  Fungi that invade skin, hair, nails are classified as?
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B.
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D.
E.
6.  Fungi that are localized and enter by trauma are classified as?
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B.
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7.  Fungi that are more virulent and cause disease in healthy hosts are classified as?
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8.  Fungi that infect only infect compromised hosts are clasified as?
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B.
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E.
9.  Which part of the fungal cell should a drug target so as to cause the least amount of damage to the human host?
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B.
C.
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10.  Which antifungal drug binds to ergosterol in the fungal membrane and forms pores in the membrane?
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11.  Amphotericin causes the cell to be leaky, which alters its permeability to which of the following?
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D.
12.  A person can only get a certain amount of Amphotercin in his/her lifetime.
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B.
13.  Which drug do fungi take it up using a permease that our cells do not make.  It gets incorporated into the fungal RNA in place of uracil. 
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14.  The fungal cells can develop a resistance to *this drug* if given by itself, so it is usually given in combination with Amphotericin B
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D.
15.  This drug is good for fungal meningitis since it can enter the CNS.
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E.
16.  Which antifungal drug Blocks squalene epoxidase enzyme to prevent squalene conversion to ergosterol. 
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B.
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17.  Which of the following are characteristic of terbinafine?
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B.
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D.
18.  Which antifungal drug inhibits cytochromes (cytochrome P450)?  This prevents ergosterol formation, which disrupts membrane function and growth
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19.  Which antifungal drug can have the following side effects?males – may develop breastsfemales – irregular menstrual cyclesliver toxicity
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20.  Thiazoles have the same SE but are less toxic than imidazoles
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B.
21.  Which antifungal drug Inhibits β-(1,3)-D-glucan synthesis, which usually makes the cross-bridges in the fungal cell wall.  Therefore cell wall formation is inhibited
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B.
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D.
E.
22.  Which of the following are Imidazoles that  are used as–topical replacements for nystatin 
A.
B.
C.
D.
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23.  Fluconazole is used to treat meningitis, because it can attain good CNS levels
A.
B.
24.  Echinocandins is a class of antifungals that act as a fungicidal for Candida and also work against Aspergillus
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B.
25.  Nystatin is a polyene similar to Amphotericin B.
A.
B.
26.  Which of the following are true about Pityriasis Versicolor?
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B.
C.
D.
E.
27.  Which 3 genera are known as Dermatophytes
A.
B.
C.
D.
E.
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28.  Cutaneous Mycoses are also called Called tineas or ringworms
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B.
29.  Which of the following are not correctly matched?
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E.
F.
30.  Which of the following shows up as typical “ringworm” lesions
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B.
C.
D.
31.  Which of the following are true about treatment of tinea corporis?
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B.
C.
D.
E.
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32.  Which of the following is  mostly seen in children before puberty?
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B.
C.
D.
33.  Which of the following is NOT true regarding treatment of tinea capitis?
A.
B.
C.
D.
E.
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34.  Tinea pedis is the most prevalent dermatophytosis in U.S.
A.
B.
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35.  Which of the following is a subcutaneous Mycosis known as “rose-handler’s” disease
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B.
C.
D.
36.  Which of the following is the cause of sporotrichosis?
A.
B.
C.
D.
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37.  Treat Sporotrichosis caused by  Sporothrix schenckii  with newer azole, e.g. itraconazole
A.
B.
38.  What is the primary focus of infection for Systemic Mycoses
A.
B.
C.
D.
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39.  Which systemic mycosis is usually found in the oil of southwest U.S., Mexico, South America and is referred to as San Joaquin Valley Fever?
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B.
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D.
40.  Which of the following is not true regarding Histoplasma capsulatum
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B.
C.
D.
E.
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41.  Which of the following is not dimorphic and is the only medically important encapsulated yeast?
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B.
C.
42.   Histoplasmosis is the hallmark infection of AIDS patients
A.
B.
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43.  Cryptococcosis may mimic brain tumor, abscess, or MS
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B.
44.  Which of the following is true regarding Cryptococcosis Treatment
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B.
C.
D.
E.
45.  A diaper rash is also known as a candidiasis infection.
A.
B.
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