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Human Genetics: 2

60 Questions  I  By Cralston
Genetics Quizzes & Trivia

  
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1.  Which of the choices best describes macroevolution?
A.
B.
C.
D.
2.  DNA analysis to determine genetic indentity applies
A.
B.
C.
D.
3.  A suspect's guilt seems highly likely when a very rare combination of markers is
A.
B.
C.
D.
4.  Which choice describes a biological population?
A.
B.
C.
D.
5.  All of the genes in a population comprise its
A.
B.
C.
D.
6.  CODIS is
A.
B.
C.
D.
7.  Principles of population genetics must be applied to determine identity based on DNA profiling because
A.
B.
C.
D.
8.  If one person in 50 is a carrier of an autosomal recessive disorder in a population, the cahnce tha an unrelated man and woman are both carriers is
A.
B.
C.
D.
9.  Who invented DNA profiling?
A.
B.
C.
D.
10.  Mitochondrial DNA is helful in obtaining a DNA profile for very degraded genetic material because
A.
B.
C.
D.
11.  In a population in Hardy-Weinberg equilibrium, 75 percent of the individuals have a dominant allele for a particular genen (p+0.75) and 25 percent have a recessive allele (q=0.25). The proportion of homozygous recessive individuals in the F1 generation will be
A.
B.
C.
D.
12.  If the incidence of an autosomal recessive condition is 1/3600 live births, what is the carrier frequency?
A.
B.
C.
D.
13.  Which of the folowing would not alter a gene's frequency in a population?
A.
B.
C.
D.
14.  Frequency of an X-linked recessive allele in males equals
A.
B.
C.
D.
15.  If the incidence of Tay-Sachs is 1/3600 Ashkenazim births, what is the heterozygote (carrier) freuency?
A.
B.
C.
D.
16.  In order to identify (or rule out identity) from a DNA sample that is a mixture, the investigator should know
A.
B.
C.
D.
17.  VNTRs and STRs differ in that
A.
B.
C.
D.
18. 
 
Frequency of an X-linked recessive allele in males equals
A.
B.
C.
D.
19.  The allele T is in 85 percent of a population (p=0.85). According to the Hardy-Weinberg equation, what percentage of the population will have the recessive allele t (q=?)?
A.
B.
C.
D.
20.  A "cold hit" refers to
A.
B.
C.
D.
21.  Hardy-Weinberg equilibrium is possible only if the population is
A.
B.
C.
D.
22.  In the Hardy-Weinberg equation, 2pq refers to
A.
B.
C.
D.
23.  Principles of population genetics must be applied to determine identity based on DNA profiling because
A.
B.
C.
D.
24.  Gene flow is the
A.
B.
C.
D.
25.  In a population in Hardy-Weinberg equilibrium, the frequency of recessive alleles will _______ over time.
A.
B.
C.
D.
26.  For a very rare inherited disease, the frequency of heterozygotes in a population is
A.
B.
C.
D.
27.  The parts of the genome that are used in markers of identity in DNA profiling
A.
B.
C.
D.
28.  Which group is used to calculate the frequency of an allele in a population?
A.
B.
C.
D.
29.  If the incidence of an autosomal recessive condition is 1/3,600 live births, what is the carrier frequency?
A.
B.
C.
D.
30.  DNA profiling was less useful in identifying remains from the 2004 tsunami than in criminal cases because
A.
B.
C.
D.
31.  A social characteristic that can create clines is
A.
B.
C.
D.
32.  A small group of islanders leave "island A" and travel to "island B." After several generations on island B, a researcher finds that a large percentage of the population is left-handed. Left-handedness is a relatively rare trait on island A. A genetic event that explains this is
A.
B.
C.
D.
33.  The frequency of the allele that causes sickle cell disease is higher in some populations than in others because
A.
B.
C.
D.
34.  Darwin thought that all natural selection was negative. However, we have since learned that positive selection is a powerful force, and it
A.
B.
C.
D.
35.  The population of HIV variants in a person's body changes during the course of infection due to
A.
B.
C.
D.
36.  In human populations, Hardy-Weinberg equilibrium is seen
A.
B.
C.
D.
37.  ___in the mycobacterium tuberculosis population reduced the incidence and virulence of tuberculosis in the early twentieth century
A.
B.
C.
D.
38.  Many alleles cause PKU. A unique mutation found only in Yemenite Jews is probably
A.
B.
C.
D.
39.  To determine the evolutionary history of a gene, geneticists assume that the most prevalent alleles in a population
A.
B.
C.
D.
40.  A sharp cline may indicate
A.
B.
C.
D.
41.  Resistance of sickle cel disease carriers to malaria illustrates
A.
B.
C.
D.
42.  In the science fiction film When Worlds Collide, 100 individuals are selected to leave a doomed Earth in a spaceship to re-establish humanity elsewhere. This scenario illustrates
A.
B.
C.
D.
43.  Memers of two populations in different parts of the world have the same form of inherited breast cancer. The affected individuals in each population have only one specific mutation, but it is different between the two populations. An explanation for this mutation difference among these populations is
A.
B.
C.
D.
44.  A founder effect within a founder effect occurred among the
A.
B.
C.
D.
45.  The gradual change in specific human mitochondrial DNA sequences along a river illustrates
A.
B.
C.
D.
46.  A more recently developed cancer treatment is
A.
B.
C.
D.
47.  Cancer cells
A.
B.
C.
D.
48.  BRCA1 and BRCA2 mutations
A.
B.
C.
D.
49.  The connection between stem cells and cancer is that
A.
B.
C.
D.
50.  A breast cancer test for HER2 considers
A.
B.
C.
D.
51.  Genes that normally prevent cell division are
A.
B.
C.
D.
52.  Growth of new blood vessels in and around tumors is called
A.
B.
C.
D.
53.  Matthew has the inherited form of the eye cancer retinoblastoma. His disease is caused by
A.
B.
C.
D.
54. 
 
Cancer does not typically follow a Mendelian pattern of inheritance because it is usually caused by
A.
B.
C.
D.
55. 
 
The first mutation typically detected in FAP colon cancer is
A.
B.
C.
D.
56.  Several genes that cause inherited forms of breast cancer have _____ in common.
A.
B.
C.
D.
57.  Loss of tumor suppression in a cell usually results from
A.
B.
C.
D.
58.  Which of these are thought to have anti-cancer benefits?
A.
B.
C.
D.
59. 
 
Which type of study would compare the incidence of colon cancer among Japanese and Americans of Japanese descent?
A.
B.
C.
D.
60.  Sporadic cancers result from
A.
B.
C.
D.
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