Steps of Krebs Cycle

From 9th chapter of Campbell's AP Biology textbook, 7th edition

8 cards   |   Total Attempts: 182
  

Cards In This Set

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Step one
Unstable acetyl CoA bond breaks, CoA relased acetyl group bonds 4-C oxaloacetate -> 6-C Citrate
Step two
H20 is removed, another is added back to convert citrate to its isomer, isocitrate
Step three
Isocitrate loses CO2 and remaining 5-C is oxidized (ketoglutarate) to reduce NAD+ to NADH
Step four
Multienz. compx catalyzes: removal of C02, oxidat. of 4-C compound to reduce NAD+ to NADH, CoA attaches to high energy bond to make succinyl CoA
Step five
Phosphate group is transferred to GDP (->GTP) and then to ADP (->ATP). Remain 4-C compound is succinate
Step six
Succinate is oxidized into fumarate as 2Hs are transferred to FAD (->FADH2)
Step seven
Water is added to fumarate which rearranges its bonds to become malate
Step eight
Malate is oxidized into oxaloacetate as 1H is transferred to NAD (->NADH)