Specific Antidotes


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Acetaminophen
 
N-acetylcysteine
Salicylates
 
NaHCO3 (alkalinize urine), dialysis
Amphetamines (basic)
 
NH4Cl (acidify urine)
Anticholinesterases, organophosphates
 
Atropine, pralidoxime
Antimuscarinic, anticholinergic agents
 
Physostigmine salicylate
β-blockers
 
Glucagon
Digitalis
 
Stop dig, normalize K+, lidocaine, anti-dig Fab fragments, Mg2+
Iron
 
Deferoxamine
Lead
 
CaEDTA, dimercaprol, succimer, penicillamine
Arsenic, mercury, gold
 
Dimercaprol (BAL), succimer
Copper, arsenic, gold
 
Penicillamine
Cyanide
 
Nitrite, hydroxocobalamin, thiosulfate
Methemoglobin
 
Methylene blue, vitamin C
Carbon monoxide
 
100% O2, hyperbaric O2
Methanol, ethylene glycol (antifreeze)
 
Ethanol, dialysis, fomepizole
Opioids
 
Naloxone/naltrexone
Benzodiazepines
 
Flumazenil
TCAs
 
NaHCO3 (serum alkalinization)
Heparin
 
Protamine
Warfarin
 
Vitamin K, fresh frozen plasma
tPA, streptokinase
 
Aminocaproic acid
Theophylline
 
Beta-blocker
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