Reduced pseudocholinesterase activity

4 cards

pharmacology knowledge for primary FRCA


 
  
Created Jan 6, 2011
by
007wendy

 

 
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1
Normal enzyme: symbol, % population homozygotes, dibucaine number, paralysis duration sux
 
E1u, 94% population homozygotes, DN 75-85, fluoride number 60, normal paralysis duration
2
Atypical enzyme: symbole, % population homozygotes, dibucaine number, duration paralysis sux
 
E1a, 0.03% population homozygotes, dibucaine number 15-25, 2-4h paralysis duration
3
Silent gene, symbol, % population homozygotes, how much plasma cholinesterase?, dibucaine number,...
 
E1s, 0.001% population homozygotes, no plasma cholinesterease, DN 0, 2-4h duration paralysis
4
Fluoride-resistant gene, symbol, % population homozygotes, dibucaine number, duration paralysis...
 
E1f, 0.0001% population, DN 65-75, 1-2h paralysis sux

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