Flashcard Set Preview
| Side A | Side B | ||
| 1 |
What is the cause of Parkinson's Disease?
|
death of cells that produce dopamine
|
|
| 2 |
What are some of the manifestations of Parkinson's Disease?
|
resting tremors, pill rolling, muscle rigidity, difficulty starting movements and controlling...
|
|
| 3 |
Dopamine is ______________; Acetylcholine is ____________.
|
Dopamine is inhibitory; Acetylcholine is stimulatory.
|
|
| 4 |
What is the combination of levodopa and carbidopa, and what is its advantage?
|
Sinemet, it has higher efficacy
|
|
| 5 |
what class is levodopa (L-Dopa, Larodopa) in?
|
Dopaminergic Drugs for Parkinsonism
|
|
| 6 |
What is the short-term medical treatment of extra pyramidal side effects in the healthcare...
|
benadryl
|
|
| 7 |
What do antiparkinsonism drugs do?
|
Restore the balance of dopamine and AcH
|
|
| 8 |
What is the action of dopaminergic drugs?
|
Used to increase dopamine levels in certain areas of the brain
|
|
| 9 |
What class is levodopa (Larodopa) in?
|
Dopaminergic Agent
|
|
| 10 |
What are contraindications for dopaminergic drugs?
|
some glaucoma, some skin lesions, hypersensitivity
|
|
| 11 |
When should you use caution with dopaminergic drugs?
|
patients with severe cardiac or liver disease, renal disease, endocrine diseases or pregnancy/lactation
|
|
| 12 |
What are some side effects of levodopa?
|
hypotension, tachycardia,
|
|
| 13 |
What are some teaching points for patients using levodopa or other dopaminergic agents?
|
-It may take several months to attain therapeutic level
-Constipation
-Do not stop abruptly
-...
|
|
| 14 |
When are anticholinergic drugs used in the Parkinson's Disease process and what do they do?
|
Used early in disease to inhibit action of acetylcholine
|
|
| 15 |
What are some examples of anticholinergic drugs?
|
Cogentin, Benadryl, Artane
|
|
| 16 |
What are side effects of anticholinergic drugs?
|
dry mouth, blurred vision, tachycardia, urine retention, constipation, drowsiness
|
|
| 17 |
What are teaching points for anticholinergic drugs?
|
Constipation, relief of dry mouth, take with food/milk, see eye MD (may promote glaucoma),...
|
|
| 18 |
What are some manifestations of Alzheimer's Disease?
|
loss of memory and judgement, confusion or disorientation, loss of communication skills, loss...
|
|
| 19 |
When does Alzheimer's disease usually begin?
|
generally after age 60
|
|
| 20 |
What is the patho associated with Alzheimer's Disease?
|
Structural damage to brain, Amyloid plaques, Neurofibrillary tangles, Loss in number and function...
|
|
| 21 |
What are the goals of drug therapy with Alheimer's Disease?
|
To modestly improve ADL's, Behavior and Cognition
|
|
| 22 |
What class is benztropine mesylate (Cogentin) in?
|
Anticholinergic used for Parkinsonism
|
|
| 23 |
What does acetylcholinesterase inhibitors do?
|
inhibitors stop the destruction of Ach
|
|
| 24 |
What are some side effects of acetylcholinesterase inhibitors (parasympathomimetics)?
|
N/V/D,
Cognex: Hepatotoxicity
Exelon: Weight loss
|
|
| 25 |
What does Memantine do in the use for Alzheimer's Disease?
|
Protects against brain cell destruction
|
|
| 26 |
What are some teaching points for acetylcholinesterase inhibitors?
|
Take with food/milk, Report changes in mood/mental status, Keep follow up appts, Dry mouth...
|
No comments yet! Be the first to add a comment below!
Please login to post comments.
After login, we will forward you back to this flashcard.