Pharmacology - Module 1 TEST 1

General pharmacology, mostly terms, test 1

106 cards   |   Total Attempts: 184
  

Cards In This Set

Front Back
Hyporeactivity that occurs from chronic overexposure to a drug (eg- opioid or alcohol) a) therapeutics b) pharmacodynamic tolerance c) cross tolerance e) idiosyncrasy
B) pharmocodynamic tolerance this is attributed to neuronal adaptation or cellular tolerance
A patient is tolerant of morphine and is likely to display a tolerance to demerol. This is an example of: a) pharmacodynamic tolerance b) cross tolerance c) enzyme induction this is an example of what?
B) cross tolerance - tolerance developed btwn drugs w/in the same class or different classes that produce similar pharmacologic effects. another example is alcohol and inhaled anesthetics
In regards to metabolic tolerance - a decreased response to a dose of a drug may also develop because of... a) a decrease in the rate of elimination of the drug. b) an increase in the rate of elimination of the drug.
B) an increase in the rate of elimination of the drug.
Drugs that increase elimination or metabolism of itself a) enzyme inducer b) enzyme inhibitor
A) enzyme inducer
Metabolic tolerance according to Lehne is defined as decreased response to a dose of a drug may also develop because of an increase in rate of elimination of the drug. this is termed: a) enzyme inhibtion b) enzyme induction c) down regulation d) up regulation
B) enzyme induction
Your elderly patient with COPD uses Salmeterol 2 puffs Q 12 hrs. It appears his response to albuterol inhalations for acute attacks of bronchospasm is less than before he started using salmeterol. This tolerance is often called: a) pharmacodynamic tolerance b) up regulation c) down regulation d) tachyphylaxis
C) down regulation A reason for a need in increased dose is a decreased number or sensitivity of receptor sites after continued dosing.
In response to constant depression of receptors (as with beta blockers), the body may either increase the number of receptors or increase the sensitivity of receptors   is termed: a) cross tolerance b) up regulation c) down regulation d) tachphylaxis
C) up regulation   1 of the reasons why some drugs need to be dc'd slowly
A rapid tolerance to the effect of some drugs (brought on by repeated dosing over a short pd of time) a) cross tolerance b) up regulation c) down regulation d) tachyphylaxis
D) tachyphylaxis
Describes an unusual effect of a drug   usually occurs in very small % of pts, and may not be related to the dose of the drug a) adverse reaction b) side effect c) idiosyncrasy d) toxic effect
C) idiosyncrasy
Any action of the drug other than the desired therapeutic effect a) adverse reaction b) side effect c) idiosyncrasy d) toxic effect
B) side effect
A noxious, unintended, and indesirable effect that occurs at normal drug doses a) adverse reaction b) side effect c) idiosyncrasy d) toxic effect
A) adverse effect
Effect (usually unexpected) that is produced by large doses of the drug. a) adverse reaction b) side effect c) idiosyncrasy d) toxic effect
D) toxic effect
On prescriptions, is it ok to write Refill PRN?
No   it is interpreted different ways
What 5 things should appear in the heading of a prescription?
Prescriber's name, professional degree, address, office #, and date writtn   it may also include the DEA #
On the prescription the pt id should include
Name address and occasionally age if very young or old.   allergies may be included here