Flashcard Set Preview
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| 1 |
These two natural enzymes degrade catecholamines
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MAOCOMT
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| 2 |
How does MAO work?
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deaminationNH2 --> COOH
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| 3 |
COMT1. mechanism2. location
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1. Methylation2. kidney, liver
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| 4 |
Best tool to dx pheochromotytoma?What enzyme produces this IM?
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MetanephrineCOMT
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| 5 |
Tyramine --> octapamine can be made into a false transmitter by what enzyme?What normally...
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DBHMAOMAOi--> less epi --> decrease BP
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| 6 |
How is tyramine gotten by the body?What does it turn into (i.e. false transmitter)?
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wine / cheese / beer / caviar / dairyOctopamine
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| 7 |
Why does the body normally handle tyramine OK?
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MAO destroys it
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| 8 |
What would happen to BP if taken a MAOi and eat tyramine?
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Tyramine --> octopamineOctopamine releases epinephrine (indrect symphathomimietic)Huge increase...
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