Perfusion I - Week 12 Acid/Base Chemistry (Sabina)

20 cards

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Created Dec 1, 2010
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perfusionschool

 

 
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1
Normal pH is 7.35-7.45. What is considered acidosis and what is considered alkalosis?
 
pH < 7.35 (an increase in H+) = acidosis   pH > 7.45 (a decrease in H+) = alkalosis
2
What does the equation for the Law of Mass Action say?   K HB = [H+][B]/[HB]
 
At equilibrium, the ratio of the product of the concentration of the dissociated [H+] and the...
3
What is the Henderson Hasselbalch equation?
 
[H+] = K HB x [HB]/[B]
4
What percentage of total buffering capacity is in body fluids?
 
60%
5
What percentage capacity are the following buffer systems in our body?   hemoglobin/oxyhemoglobin: plasma...
 
hemoglobin/oxyhemoglobin: 30% plasma proteins: (pK=7.4) 7% inorganic/organic phosphates:...
6
What do the following terms mean?   metabolic acidosis: metabolic alkalosis: respiratory...
 
metabolic acidosis: gain in H+ or loss of HCO3- metabolic alkalosis: gain in HCO3- or loss...
7
What are the primary causes of metabolic acidosis?
 
lactic acidosis ketoacidosis renal failure ingestion of base depleting drugs
8
What are the primary causes of metabolic alkalosis?
 
hypokalemia excessive vomiting massive steroid dose diuretics increased k secretion ingestion...
9
What are the primary causes of respiratory acidosis?
 
cardiopulmonary disease copd cns depression neurologic/neuromuscular diseases that weaken           ...
10
What are the primary causes of respiratory alkalosis?
 
hyperventilation hypoxemia compensation for metabolic acidosis cns stimulation emotional...
11
What are the compensatory mechanisms for acid/base disturbances?
 
> buffer systems which act immediately > respiratory compensation - controls pCO2 and...
12
What is BE?
 
The base excess is the quanitity of extra base above normal (principally bicarbonate ions)...
13
True or False   Increase in pCO2 without an increase in HCO3- so as to decrease the...
 
True
14
True or False   A pH change due primarily to changes in HCO3- (and other anions) is...
 
True
15
The following symptoms signify which of the following - metabolic acidosis, respiratory acidosis,...
 
respiratory acidosis
16
The following symptoms signify which of the following - metabolic acidosis, respiratory acidosis,...
 
respiratory alkalosis
17
The following symptoms signify which of the following - metabolic acidosis, respiratory acidosis,...
 
metabolic alkalosis
18
True or False   Acids are substances capable of donating protons.   Bases are...
 
True
19
What is the normal partial pressure of Oxygen (pO2) and what does it reflect?
 
Normal value is between 80-104 mmHg   It reflects the amount of oxygen dissolved in...
20
What is a normal value for arterial oxygen saturation and what does it tell us?
 
Normal saturation is >94%   This measure is of the percentage of O2 combined with...

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