Flashcard Set Preview
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| 1 |
Normal pH is 7.35-7.45. What is considered acidosis and what is considered alkalosis?
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pH < 7.35 (an increase in H+) = acidosis
pH > 7.45 (a decrease in H+) = alkalosis
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| 2 |
What does the equation for the Law of Mass Action say?
K HB = [H+][B]/[HB]
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At equilibrium, the ratio of the product of the concentration of the dissociated [H+] and the...
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| 3 |
What is the Henderson Hasselbalch equation?
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[H+] = K HB x [HB]/[B]
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| 4 |
What percentage of total buffering capacity is in body fluids?
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60%
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| 5 |
What percentage capacity are the following buffer systems in our body?
hemoglobin/oxyhemoglobin:
plasma...
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hemoglobin/oxyhemoglobin: 30%
plasma proteins: (pK=7.4) 7%
inorganic/organic phosphates:...
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| 6 |
What do the following terms mean?
metabolic acidosis:
metabolic alkalosis:
respiratory...
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metabolic acidosis: gain in H+ or loss of HCO3-
metabolic alkalosis: gain in HCO3- or loss...
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| 7 |
What are the primary causes of metabolic acidosis?
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lactic acidosis
ketoacidosis
renal failure
ingestion of base depleting drugs
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| 8 |
What are the primary causes of metabolic alkalosis?
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hypokalemia
excessive vomiting
massive steroid dose
diuretics
increased k secretion
ingestion...
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| 9 |
What are the primary causes of respiratory acidosis?
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cardiopulmonary disease
copd
cns depression
neurologic/neuromuscular diseases that weaken
...
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| 10 |
What are the primary causes of respiratory alkalosis?
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hyperventilation
hypoxemia
compensation for metabolic acidosis
cns stimulation
emotional...
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| 11 |
What are the compensatory mechanisms for acid/base disturbances?
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> buffer systems which act immediately
> respiratory compensation - controls pCO2 and...
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| 12 |
What is BE?
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The base excess is the quanitity of extra base above normal (principally bicarbonate ions)...
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| 13 |
True or False
Increase in pCO2 without an increase in HCO3- so as to decrease the...
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True
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| 14 |
True or False
A pH change due primarily to changes in HCO3- (and other anions) is...
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True
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| 15 |
The following symptoms signify which of the following - metabolic acidosis, respiratory acidosis,...
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respiratory acidosis
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| 16 |
The following symptoms signify which of the following - metabolic acidosis, respiratory acidosis,...
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respiratory alkalosis
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| 17 |
The following symptoms signify which of the following - metabolic acidosis, respiratory acidosis,...
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metabolic alkalosis
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| 18 |
True or False
Acids are substances capable of donating protons.
Bases are...
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True
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| 19 |
What is the normal partial pressure of Oxygen (pO2) and what does it reflect?
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Normal value is between 80-104 mmHg
It reflects the amount of oxygen dissolved in...
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| 20 |
What is a normal value for arterial oxygen saturation and what does it tell us?
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Normal saturation is >94%
This measure is of the percentage of O2 combined with...
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