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Factors increasing p50 of oxyhb dissociation curve (right shift - increased affinity for O2)
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acidosis, raised CO2, raised temperature, increased 2,3DPG, pregnancy, HbS, altitude
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Factors decreasing p50 of oxyHb dissociation curve (left shift - decreased affinity for O2)
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low CO2, low temp, alkalosis, low 2,3DPG, methaemoglobin, foetal Hb, carbon monoxide
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