Myocardial Preservation, Acid/Base Chemistry - SR

50 cards

Perfusion


 
  
Created Dec 13, 2009
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perfusionschool

 

 
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1
What is a normal pH level?
 
7.35-7.45
2
Read the Blood Gas   pH:  7.06 pCO2: 19 O2 Sat: 89 HCO3: 3 BE: -30
 
Partially compensated Metabolic acidosis
3
Read the Blood Gas   pH:  7.25 pCO2: 90 O2 Sat: 34 HCO3: 38 BE: +5
 
Partially Compensated Respiratory Acidosis
4
Read the Blood Gas   pH: 7.36 pCO2: 20 O2 Sat: 100 HCO3: 19 BE: -7.6
 
Fully Compensated Metabolic Acidosis
5
Read the Blood Gas   pH: 7.42 pCO2: 38 O2 Sat: 100 HCO3: 25 BE: +1
 
Normal Blood Gas
6
Read the Blood Gas   pH:  7.54 pCO2: 22 O2 Sat: 100 HCO3: 25 BE: +1
 
Respiratory alkalosis
7
Read the Blood Gas   pH: 7.45 pCO2: 24 O2 Sat: 100 HCO3: 21 BE: -4
 
Fully compensated Respiratory alkalosis
8
Read the Blood Gas   pH: 7.50 pCO2: 40 O2 Sat: 100 HCO3: 29 BE: +5
 
Metabolic Alkalosis
9
Read the Blood Gas   pH: 7.47 pCO2: 60 O2 Sat: 100 HCO3: 30 BE: +8
 
Partially Compensated Metabolic Alkalosis
10
Read the Blood Gas   pH: 7.42 pCO2: 20 O2 Sat: 100 HCO3: 22 BE: -3.7
 
Fully compensated Respiratory Alkalosis
11
Read the Blood Gas   pH: 7.79 pCO2: 40 O2 Sat: 100 HCO3: 33 BE: +12
 
Metabolic Alkolosis Not compensated
12
Read the Blood Gas   pH:  7.0 pCO2: 66 O2 Sat: 100 HCO3: 25 BE: +1.0
 
Respiratory Acidosis
13
Read the Blood Gas   pH: 7.35 pCO2: 70 O2 Sat: 100 HCO3: 30 BE: +9
 
Fully Compensated Respiratory Acidosis
14
Read the Blood Gas   pH: 7.42 pCO2: 35 O2 Sat: 100 HCO3: 25 BE: +1.0
 
Normal
15
Briefly describe the myocardium.
 
Thick muscle layer of the heart that works to contract the heart Cardiac muscle
16
Which filaments of a sarcomere are responsible for contraction?
 
Thick Myosin filaments Thin actin filaments
17
What ion is necessary from muscle contraction?
 
Calcium
18
What is needed for calcium to disassociate from the actin?
 
ATP
19
How many moles of ATP does Anaerobic metabolism yield?
 
2 moles of ATP
20
What will happen to the pH if there is an accumulation of lactate?
 
The pH will decrease
21
What types of things can Ischemia lead to?
 
Depletion of my cardial high energy phosphates Intracellular and extra cellular acidosis Inhibition...
22
How do you prevent ischemia while on CPB?
 
Decrease oxygen demand -Arrest the heart -hypothermia
23
A cold fibrillating heart uses (more/less) oxygen than a normal heart beating at 37 degrees...
 
More. 1cc O2/100g/min at  37 C 2.0 O2/100g/min at 22 C
24
Name 3 methods of Myocardial Preservation.
 
Intermittent aortic occlusion Ventricular fibrillation Cardioplegia myocardial protection
25
What is a good indicator of adequate cardioplegia delivery?
 
Myocardial Temperature
26
Which of the following is not true regarding Intermittent Aortic Occlusion?   a. ...
 
b. Hypothermia is used to decrease oxygen demand
27
Which of the following is not a goal of Cardioplegia?   a. Quiet, Motionless field b. ...
 
B. Bloodless field
28
Where is proper placement of an antegrade cardioplegia cannula?
 
Between the cross clamp and aortic valve
29
Where is the proper placement of a retrograde cardioplegia cannula?
 
In the R. heart in the coronary sinus
30
Regarding pressure, when delivering retrograde cardioplegia what pressure range should you...
 
20-40 mmHg
31
Name two types of cardioplegia.
 
Crystalloid solution Blood cardioplegia
32
What is an advantage of the crystalloid plegia solution?
 
Decreased viscosity for better distribution
33
What is an advantage blood cardioplegia?
 
Effective buffer Better recovery of myocardial function Decreases edema
34
Advantages of Cold Cardioplegia
 
Reduction of MvO2 Electrical silence maintained after plegic agent is washed out Maintains...
35
Disadvantages of Cold Cardioplegia
 
Delay in function and metabolic recovery of the heart Reduced enzyme function Alteration...
36
What are some concerns regarding continuous delivery of warm cardioplegia?
 
Increased blood in operative field Increased volumes of plegia Interuptions can lead to myocardial...
37
Regarding cardioplegia, describe a "hot shot".
 
Used to resuscitate the myocardium which will decrease reperfusion injuries Reversal of hypothermic...
38
Name 6 additives in cardioplegia
 
Potassium Calcium Magnesium Lidocaine Glutamate/Aspertate Nitroglycerine Albumin, glucose,...
39
What is the role of Potassium as an additive in cardioplegia?
 
Increased extracellular K causing asystole by depolarizing the cell membrane Lowers resting...
40
What is the role of Calcium as an additive in cardioplegia?
 
Extracellular hypocalcemia produces arrest by limiting the ionic calcium available to trigger...
41
What roles does magnesium have as a cardioplegia additive?
 
Inhibit release of Ca by sarcoplasmic reticulum Competes with Ca at ATP activation sites Modulates...
42
What is the role of Lidocaine as a cardioplegia additive?
 
Membrane stablization - Decrease post arrest arrhythmias - Prevent edema - Blocks Na permeability...
43
What is the role of Glutamate/Aspertate as a cardioplegia additive?
 
Provide fuel for energy production
44
What is the role of Nitroglycerine as a cardioplegia additive?
 
Prevent/reduce the vasoconstrictive effects of particulate contaminants
45
A blood gas shows a decreased pCO2 and an increased pH
 
Respiratory Alkalosis
46
A blood gas shows an increase in pCO2 and a decreased pH
 
Respiratory Acidosis
47
A gain in H or loss of HCO3
 
Metabolic Acidosis
48
A gain in HCO3  or loss of H
 
Metabolic Alkalosis
49
What percentage of the bicarb/buffer system in our bodies Hemoglobin/oxyhemoglobin?
 
30%
50
What percentage of the bicarb/buffer system in our bodies plasma proteins?
 
7.4%

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