Muscle relaxants and anticholinesterases + atropine/hyoscine

6 cards

pharmacology knowledge for primary FRCA


 
  
Created Dec 21, 2010
by
007wendy

 

 
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1
what type of molecule is neostigmine
 
quaternary amine
2
what type of molecule is physostigmine?
 
tertiary amine, absorbed more readily than neostigmine
3
What are the metabolites of atracurium?
 
Hoffmann: laudanosine and quaternary monoacrylate, ester hydrolysis: quaternary alcohol + quaternary...
4
What are the metabolites of vecuronium?
 
3- and 17-hydroxyvecuronium and 3,17 dihydroxyvecuronium
5
What type of molecule is glycopyrrolate? Can it cross BBB?
 
Quaternary (4) amine, charged and cannot cross BBB
6
What type of molecules are atropine and hyoscine? Can they cross BBB?
 
tertiary amines, esters. Can cross BBB

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