Flashcard Set Preview
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| 1 |
Warren Weaver
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-director of Rocketfeller Foundation-first to use the term molecular biology in 1938
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Eduard Buchner
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-1860-1917-devlievered the death knell to vitalism when he demostrated that fermentation of...
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Molecular biology
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study of the structure and function of proteins
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Central Dogma
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-envisioned by Crick in 1958-drawn in 1970-solid arrows represent probable transfers, dotted...
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Fredrich Miescher
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1844-1895-Successfully developed a method to isolate intact WBC from bandages-identify and...
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Sidney Altman
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-discovered RNase P, the enzyme that generates tRNA molecules from longer precursos-first to...
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Fredrick Sanger
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developed orignal method of sequencing DNA in 1975-dideoxy
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Leory Hood
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-developed modern sequencing technique in 1986 using different fluorescent tags for each nucleotide
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Walter Gilbert
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discovered different sequencing technique in 1975 that is not used today
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| 10 |
Base pairs
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3.2 x 10^9
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Protein coding genes
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20,488
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Percentage of human base pairs in human genome that code for polypeptides
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1.5%
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| 13 |
Albrecht Kossel
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-ID nucleotides
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Phoebus Levene
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-tetranucleotide hypothesis
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william astbury
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1938-first to study DNA by x-ray diffraction-determined that bases were at right angles to...
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Alexander Todd
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1951-used synthetic methods and RNase to demonstrate that long polypeptie chains connected...
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| 17 |
Maurice Wilkins
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-first to study DNA seriously using x-ray diffraction-took sharp DNA photos-saw 2 forms of...
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| 18 |
Rosalind Franklin
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-showed 2 different DNA diffraction patterns-took photo 51 in may 1952-pattern B was helix
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| 19 |
Jerry Donohue
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-Feb. 27, 1953-Showed watson the correct tautomers of T and G
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| 20 |
Erwin Chargaff
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-Analysis of base composition of nucleic acids-measured amounts of dA, dT, dC, dG in DNA to...
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| 21 |
Erwin Schroedinger
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1933-published what is life-which influcened many physicists into biology
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| 22 |
Watson and Crick
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-built DNA models to determine final strcuture of DNA-proposed that 2 nucleotide chains are...
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