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---PICORNAVIRUSES---
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---PICORNAVIRUSES---
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| 2 |
What are the 4 genres in this family that cause most human diseases?
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1. Enteroviruses2. Rhinoviruses3. Hepatoviruses4. Aphthoviruses
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True/False:Enteroviruses are stable at a pH of 3.
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True
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Picornaviruses are internalized by what process?
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Endocytosis
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Where do viruses in the family Picornaviruses replicate?
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In the cytoplasm
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During the replication process of Picornaviruses, the polyprotein is cleaved by what polymerase?
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viral RNA dependent RNA polymerase
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True/False:In order to replicate the Picornavirus, the polymerase must develop a positive (+)...
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False; negative strand template is developed
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True/False:Most enteroviruses are considered cytolytic.
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True
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What type of Picornavirus binds to ICAM-1 receptors on respiratory epithelial cells?
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Rhinovirus
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Anatomically, where does the majority of rhinovirus replication take place?
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In the nose
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What substances, secreted by the infected cells, cause "runny nose?"
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Bradykinin & Histamine
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| 12 |
What are four viruses in the subfamily Enterovirus?
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1. Polio virus2. Coxackie virus3. Echo virus4. Entero virus
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| 13 |
What are common symptoms of Acute Rhinitis?
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nasal obstruction, sneezing, rhinorhhea, pharyngitis, headache and malaise
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True/False:Rhinoviruses, when accompanied by secondary bacterial infection, are also associated...
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True
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What substance do virally infected cells secrete in order to limit the progression of the rhinovirus...
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Interferon
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