Microbio: Lecture 9    

19 cards

basic understanding of DNA replication, protein synthesis; how mutations develop


 
Password:       
 
  
Created Mar 2, 2010
by
diana429

 

 
Table View
 
Download
 
Print

Flashcard Set Preview

  Side A   Side B
1
who discovered the molecular structure of DNA?
 
James Watson and Francis Crick
2
DNA helicase
 
unwinds and seperates parental strand in a small area of the chromosome
3
nucleoside triphosphates
 
pre-formed nucleotides (base, sugar, phosphate) in the cytoplasm; building blocks of DNA
4
DNA polymerase 
 
adds nucleotides to the 3' end of the daughter strand; moves towards the replicaiton fork...
5
1'3'5'
 
#1 carbon; base is attached here#3 carbon; has an OH group#5 carbon; phosphate group attached...
6
lagging strand 
 
RNA primer binds to the 3' end; synthesized in pieces called Okazaki fragments; then joined...
7
semi-conservative replication 
 
finished products consists of one parent strand and one daughter strand
8
transcription 
 
transfer of information from DNA to RNA; A dictates U (uracil) in mRNA-- sense strand serves...
9
translation
 
protein synethesis; sets of three nucleotides (codons) specify each amino acid; takes place...
10
degeneracy
 
most amino acids are specified by several codons (64 possible codons but only 20 amino acids)
11
DNA replication in eukaryotes
 
DNA has regions that code for proteins (exons) and regions that don't (introns); all nucleotides...
12
stop codons
 
UAA, UAG, UGA specify "stop"; signal end of translation 
13
start codon
 
AUG specifies methionine and sinals beginning of translation
14
constitutive production
 
60-80% of enzymes are produced constantly 
15
repression
 
transcription of mRNA for regulated enzymes is inhibited by repressors (regulatory...
16
induction
 
trascription of mRNA for a regulated gene is activated; inducers cause inducible enzymes...
17
operon model
 
developed by Francis Jacob, Jacques Monrod and Andre Lwoff; on a strand of bacterial DNA,...
18
Lac operon
 
in e. coli; three enzymes must be made in order to digest lactose: B-galactosidase (splits...
19
tryptophan
 
amino acid; when in excess, binds to and actives a repressor; this complex binds to the tryptophan...

No comments yet! Be the first to add a comment below!

Please login to post comments.
After login, we will forward you back to this flashcard.

Upgrade and get a lot more done!
Upgrade