Flashcard Set Preview
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| 1 |
some pathogens can alter cell surface chemistry or change their antigens, this is called
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antigenic shift or phase variation
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| 2 |
pathogens decorate their surface with molecules that mimic host cell surfaces
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molecular mimicry
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| 3 |
pathogens secrete ___ to kill leukocytes, and some live with in leukocytes
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leukocidin
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| 4 |
pathogens secrete ____ to digest antibodies in response to host's immunoglobulins
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proteases
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| 5 |
the specific proteases that pathogens secrete are called?
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Ig proteases
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| 6 |
Once the pathogen evades the immune system it will damage host cells by ____ or ____
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direct damage- toxin or enzyme productionindirect damage- host inflammatory response
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| 7 |
poisonous substances produced by mircoorganisms which are often responsible for much of the...
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Toxins
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| 8 |
____ are secreted by living microorganisms and may be gram positive or gram negative
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Exotoxins
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| 9 |
____ are cell associated and only gram negative
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Endotoxins
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| 10 |
___ are a type of toxin that is a protein
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Exotoxins
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| 11 |
this type of toxin is lipid A component of LPS
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Endotoxins
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| 12 |
___ are heat-labile (inactivated easily by boiling)
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Exotoxins
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| 13 |
____ are heat stable (will withstand autoclaving)
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Endotoxins
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| 14 |
___ must be removed by ultrafiltration or through use of pyrogen-free fluids
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Endotoxins
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| 15 |
_____ can be converted to toxoids (pathogenic properties lost- immunogenic properties remain)
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Exotoxins
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