Mic 205- Bacterial Shapes and Arrangement

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What are the 3 main shapes of bacterial cells?
Coccus - round
bacillus - rod shaped
spiral - curved
Arrangement: diplo-
Pairs
Arrangement: strepto-
Chains
Staphyl-
Clusters
Positions within cell
Central
terminal
subterminal (near end)
Sticky sugar substance; sometimes protein
Capsule

-present or absent
Cell surface includes:
Cell wall (LPS)
flagella
fimbriae
pili
capsules
-adherence to host tissues
-resist phagocytosis
-immune response
-induce inflammation
-resistant to drugs
Important in pathogenesis
Extracellular gelatinous substance (viscous polymer)
Glycolalyx
-surrounds cells
-most are polysaccharides (sugars), some are polypeptides (proteins) in loose gel
-in both G+ and G- bacteria
Glycolalyx
-adhesion/attachment- to other cells (bac + host) as well as biofilm
-reserve of nutrients or protection against dessication
-virulence factor
Virulence factor
-intensity of disease produced by pathogen capsule prevents phagocytosis by immune system, also important for adherence to host tissues
Virulence factor
-functional consortium of bacteria organized within an extensive exopolymer matrix
-extremely resistant to clearance by human immune system and antibiotics
-many human disease associated with these (up to 65%)
Biofilms
3 types of appendages:
Flagella
fimbriae
pili
Flagella
fimbriae
pili
Motility
adhesion (sometimes aka common pili)
(sex pili)