Major Histocompatibility Receptors

8 cards

        Via transcription factors such as RFX, Cytokines, such as Interferons can cause the upregulation of Class 1 and Class 2 molecules..Steroids can cause a downregulation of class II receprtos. Viruses can cause downregulation of Class I receptors.


 
  
Created Jul 17, 2012
by
dr.clark

 

 
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1
Where are class 1 receptors located?
 
All cells except Rbc
2
Where are class ii located?
 
they are located on antigen presenting cells.. macrophages, dendrictic cells, B cells.
3
Where are class III located?
 
these are located on secreted proteins
4
Where are the genes for the MHC located?
 
On chromosome 6
5
MHC Hapolytes
 
These are inherited as one set of genes. from each parent. Each indv will have two hapolytes..one...
6
What is needed in order to bind to MHC Class I receptors?
 
The Class I receptors have an anchor residue on the peptide. The most important part of the...
7
What does it mean when MHC expresse polymorphism?
 
The MHC recptors express different phenotypes. There is co-dominant expression bc you get a...
8
How is the expression of MHC regulatted?
 
Via transcription factors such as RFX, Cytokines, such as Interferons can cause the upregulation...

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