KNES 485 lecture 7

49 cards

KNES 485 lect ure 7���


 
  
Created Oct 26, 2010
by
aftonw

 

 
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1
-          Contains cell bodies
 
Grey matter
2
-          Motor -         ...
 
Ventral
3
Sensory
 
Dorsal
4
-          Stretch receptors -         ...
 
2a afferent motoneuron
5
-          Groups of cell bodies for a given muscle...
 
Ventral horn
6
-          Dendritic tree is very ______
 
Extensive
7
-          Sites for excitatory and inhibitory...
 
Dendrites
8
3 G’s
 
-          GABA -         ...
9
-          Inhibitory -         ...
 
GABA, glycine
10
-          Excitatory -         ...
 
Glutamate
11
Cytoskeletal Proteins (5)
 
-          dystrohpin -         ...
12
Cytoskeletal protein functions (3)
 
1.       strengthen cell and serve as anchor for nucleus 2.      ...
13
-          predominantly structural
 
Actin
14
-          involved in all 3 cytoskeletal protein...
 
tubulin and neurofilament proteins
15
-          1 ball
 
Actin monomer
16
-          Alpha helix of actin monomers -         ...
 
Actin filament
17
-          2 forms o   Alpha o  ...
 
Tubulin
18
-          Forms a heterodimer -         ...
 
Tubulin
19
-          Made up of specialized proteins o  ...
 
Neurofilaments
20
-          Blocks axoplasmic transport by depolymerization...
 
Colchicine
21
-          Stabilizes the actin filaments
 
Phalloidin
22
-          Stabilizes microtubules
 
Taxol
23
-          Depolyermize actin
 
Cytochalasins
24
-          Induce formation of tubulin crystals...
 
Vinblastine and vincristine
25
-          Similar to skeletal muscle connective...
 
Nerve connective tissue
26
-          Around each axon
 
Endoneurium
27
-          Around fascicule
 
Perineurium
28
-          Surrounds nerve trunk
 
Epineurium
29
-          Big axon (mostly motor) =
 
Myelinated
30
-          Small axon (mostly sensory) =
 
Non-myelinated
31
-          Between fassicles
 
Blood vessels
32
-          Round -         ...
 
Artery
33
-          Oval -         ...
 
Vein
34
With injury and regeneration (3)
 
-          Schwann cells are smaller -         ...
35
-          Increases speed of AP conduction
 
Myelination
36
-          50-120 m/sec
 
Motoneurons
37
-          As big as 1 mm -         ...
 
Schwann cell
38
-          Possible exchange of substances: ATP,...
 
Schwann cell
39
-          All motor axons have ________
 
Myelin sheaths
40
-          Membrane of axon
 
Neurolemma
41
-          Layers of the Schwann cell
 
Schwann cell fingers
42
-          Gel like extracellular substance between...
 
Gap substance
43
-          Around whole Schwann cell and around...
 
BM
44
-          Motoneurons per muscle
 
< 100 - > 2000
45
-          Fibers per motor unit
 
< 10 - > 2000
46
Structure of motoneuron (8)
 
-          Soma -         ...
47
Function of cytoskeletal proteins (3)
 
1.       Strength 2.       Growth 3.      ...
48
-          Actin in _______
 
Motoneurons
49
Connective tissue in nerves (3)
 
-          Endoneurium -         ...

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